Je vais encore parler du dépistage du cancer du col de l'utérus (désolé) mais cette fois pour un truc nouveau : une étude qui compare l'usage d'un examen cytologique/frottis à l'usage d'un test HPV-HR[1].
Quand on fait un prélevement cervico-vaginal (frottis) on peut soit regarder l'apparence des cellules au microscope en laboratoire (cytologie) ou tester la présence de variants hauts risque du virus HPV dans ces cellules (test HPV-HR).
Ce que l'étude montre, c'est que chez les personnes transmasculines sous testostérone, la cytologie n'est pas plus efficace que le test HPV-HR pour réduire les faux positifs (sensibilité et sensitivité des deux pour prédire la présence d'une lésion inquiétante, CIN2+, similaires). Les deux types de tests ont une chance similaire d'indiquer une lésion (dysplasie) en cas de résultat positif (PPV, positive predictive value).

Les auteurices conseillent donc de favoriser l'utilisation des tests HPV en 1ère intention chez les personnes transmasc sous T, notamment psk les examens cytologiques sur les frottis sont plus souvent non concluants chez les personnes sous T[1,2], et passer aux tests HPV pourrait permettre d'éviter des examens pelviens supplémentaires inutiles. Bonus non-négligeable, les test HPV peuvent être des auto-prélevements vaginaux, qu'on se fait soi-même, qui tendent à être bien plus appréciées des personnes transmasculines[3].

Pour info en France, les reco HAS[4] sont d'utiliser des tests cytologiques chez les personnes (bon la HAS dit femmes...) jeunes, à 25 et 26 ans, puis à 29 ans si normal, et de passer au test HPV seulement après (à 32 ans, puis tous les 5 ans si tests négatifs), en raison d'un risque de surdiagnostic si on utilise les tests HPV chez les plus jeunes. La HAS recommande de proposer l'auto-prélevement aux personnes qui peu/pas dépistées.

[1] : Cytology and High-Risk Human Papillomavirus Testing Performance for Cervical Cancer Screening in Transmasculine Patients. Bolten K et al., 2026. https://doi.org/10.1177/15409996261433761

[2] : Cervicovaginal and Anal Self-Sampling for Human Papillomavirus Testing in a Transgender and Gender Diverse Population Assigned Female at Birth: Comfort, Difficulty, and Willingness to Use. Welsh EF et al., 2024. https://doi.org/10.1089/lgbt.2023.0336

[3] : Cytology and LGBT+ health: establishing inclusive cancer screening programs. Compton ML et al., 2022. https://doi.org/10.1016/j.jasc.2022.06.003

[4] : Évaluation de la recherche des papillomavirus humains (HPV) en dépistage primaire des lésions précancéreuses et cancéreuses du col de l’utérus, HAS, 2019. https://www.has-sante.fr/jcms/c_2806160/fr/evaluation-de-la-recherche-des-papillomavirus-humains-hpv-en-depistage-primaire-des-lesions-precancereuses-et-cancereuses-du-col-de-l-uterus-et-de-la-place-du-double-immuno-marquage-p16/ki67

#HPV #cervicalscreening #testosterone

Je râlais hier sur les étudiant·es en médecin cis qui veulent absolument étudier le dépistage du cancer du col de l'utérus et les personnes transmasc, c'est d'autant plus énervant que le sujet a été étudié en long en large et en travers, et je suis tombé sur cette revue systématique sur les facteurs limitant et facilitant l'accès aux services de prévention du cancer chez les personnes trans. La revue est chouette même si elle dit rien de révolutionnaire, bonus un joli graphique pour illustrer.

(Note : je dis personnes trans psk la revue a essayé d'inclure les personnes intersexes mais n'a quasi pas pu le faire par manque de données)

[1] : Barriers to and facilitators of cancer prevention services for transgender and gender-diverse people: A systematic review. Herrera DJ et al., 2026. https://doi.org/10.1016/j.ypmed.2026.108544 (accès libre)

#trans #screening #cervicalcancer #cervicalscreening

𝗠𝗮𝗿𝗰𝗵 𝟰𝘁𝗵 – 𝗜𝗻𝘁𝗲𝗿𝗻𝗮𝘁𝗶𝗼𝗻𝗮𝗹 𝗛𝗣𝗩 𝗔𝘄𝗮𝗿𝗲𝗻𝗲𝘀𝘀 𝗗𝗮𝘆: 𝗢𝗻𝗲 𝗟𝗲𝘀𝘀 𝗪𝗼𝗿𝗿𝘆, 𝗢𝗻𝗲 𝗕𝗶𝗴 𝗜𝗺𝗽𝗮𝗰𝘁

Human Papillomavirus (HPV) affects nearly everyone at some point. It is the most common sexually transmitted infection and linked to several cancers including cervical, throat, anal, and penile cancers. The good news? HPV is preventable and manageable through vaccination, screening, and awareness.

𝗪𝗵𝗮𝘁 𝗬𝗼𝘂 𝗡𝗲𝗲𝗱 𝘁𝗼 𝗞𝗻𝗼𝘄:

𝗛𝗣𝗩 𝗶𝘀 𝗲𝘃𝗲𝗿𝘆𝘄𝗵𝗲𝗿𝗲: Over 80% of people will get HPV in their lifetime.
𝗖𝗮𝗻𝗰𝗲𝗿 𝗥𝗶𝘀𝗸: Certain HPV types cause cancers of the cervix, mouth, throat, anus, penis, vagina, and vulva.
𝗩𝗮𝗰𝗰𝗶𝗻𝗮𝘁𝗶𝗼𝗻 𝗶𝘀 𝗸𝗲𝘆: Getting vaccinated before sexual contact can prevent nearly 90% of cervical cancer cases.
𝗦𝗰𝗿𝗲𝗲𝗻𝗶𝗻𝗴 𝘀𝗮𝘃𝗲𝘀 𝗹𝗶𝘃𝗲𝘀: Cervical screening detects early changes to cells that can be treated before they become cancer.
𝗖𝗼𝗻𝗱𝗼𝗺𝘀 𝗵𝗲𝗹𝗽 𝗯𝘂𝘁 𝗱𝗼𝗻’𝘁 𝗳𝘂𝗹𝗹𝘆 𝗽𝗿𝗼𝘁𝗲𝗰𝘁: They reduce risk but HPV can infect areas not covered by condoms.
𝗠𝗲𝗻 𝗮𝗿𝗲 𝗮𝗳𝗳𝗲𝗰𝘁𝗲𝗱 𝘁𝗼𝗼: HPV causes around 60,000 cancer cases in men annually, though no approved screening exists for men yet.
𝗦𝘆𝗺𝗽𝘁𝗼𝗺𝘀 𝗺𝗮𝘆 𝗻𝗼𝘁 𝗮𝗽𝗽𝗲𝗮𝗿: Most people don’t know they have HPV; genital warts or unusual symptoms should prompt a visit to your healthcare provider.

𝗧𝗮𝗸𝗲 𝗔𝗰𝘁𝗶𝗼𝗻:
Get the HPV vaccine if eligible.
Attend all recommended cervical screening appointments.
Use protection during sex but remember it’s not 100% protective against HPV.
Talk openly with partners and healthcare providers.
Spread awareness—knowledge is power!

Together, we can reduce the global cancer burden by about 5% — giving everyone one less worry in a world full of uncertainties.

#InternationalHPVAwarenessDay #HPVPrevention #OneLessWorry #HPVVaccine #CervicalScreening #CancerPrevention #KnowYourStatus #ProtectYourself #HPVAwareness #HealthEducation #SCABPharmacy

@carasutra It can be scary, uncomfortable or embarrassing but I still have my lovely wife now cancer free with me and for that I am so glad she always went through with these tests. #CervicalScreening

How do you feel when you open that letter? Or when the reminder pings on your phone?

I dreaded my cervical smear test for years. It’s never as terrifying as I imagine. In fact, it isn’t scary at all. I wrote about what actually happens at a cervical screening.

https://carasutra.com/2023/03/what-happens-at-smear-test-cervical-screening-exam/

#CervicalScreening #SmearTest #ReproductiveHealth #LifeUnscripted #BodyAutonomy
https://carasutra.com/2023/03/what-happens-at-smear-test-cervical-screening-exam/

What Happens At A Smear Test? My Cervical Screening Exam

What Happens At A Smear Test? My Cervical Screening Exam. Find out what really happens as I share details from my own pap smears!

Cara Sutra

Wondering how long HPV takes to cause cervical cancer? Understand the typical timeline, influencing factors, and why regular screening is crucial for prevention.
https://mrmedonlinepharmacy.mystrikingly.com/blog/how-long-does-hpv-take-to-turn-into-cervical-cancer

#HPV #CervicalCancer #WomensHealth #HPVPrevention #CervicalScreening #HealthAwareness

How Long Does HPV Take to Turn Into Cervical Cancer?

Understand HPV's progression to cervical cancer. Learn the typical timeline, risk factors, screening importance, & how prevention strategies can protect your health.

How Long Does HPV Take to Turn Into Cervical Cancer?

𝗖𝗲𝗿𝘃𝗶𝗰𝗮𝗹 𝗖𝗮𝗻𝗰𝗲𝗿 𝗣𝗿𝗲𝘃𝗲𝗻𝘁𝗶𝗼𝗻 𝗪𝗲𝗲𝗸 𝟮𝟬𝟮𝟱
𝗗𝗮𝘁𝗲: 22 - 28 January

This week, we raise awareness about cervical cancer and the vital role of screening and vaccination in prevention. Cervical cancer can be prevented, and early detection saves lives.

🌸 𝗪𝗵𝗮𝘁 𝗬𝗼𝘂 𝗡𝗲𝗲𝗱 𝘁𝗼 𝗞𝗻𝗼𝘄:

- 𝗖𝗲𝗿𝘃𝗶𝗰𝗮𝗹 𝗦𝗰𝗿𝗲𝗲𝗻𝗶𝗻𝗴: Offered to women and people with a cervix aged 25-64, this test looks for HPV and cellular changes that can lead to cancer.
- 𝗛𝗣𝗩 𝗩𝗮𝗰𝗰𝗶𝗻𝗲: Recommended for those aged 12-13 and individuals at higher risk, this vaccine protects against high-risk HPV types that can cause cervical cancer.

𝗦𝘆𝗺𝗽𝘁𝗼𝗺𝘀 𝘁𝗼 𝗪𝗮𝘁𝗰𝗵 𝗙𝗼𝗿:

- Heavier periods than usual
- Vaginal bleeding between periods, after sex, or post-menopause

If you experience any of these symptoms, don’t hesitate to consult your GP. Early intervention is key!

👉 For more information on cervical screening and vaccination, visit [your local health service website].

𝗟𝗲𝘁’𝘀 𝘄𝗼𝗿𝗸 𝘁𝗼𝗴𝗲𝘁𝗵𝗲𝗿 𝘁𝗼 𝘀𝗽𝗿𝗲𝗮𝗱 𝘁𝗵𝗲 𝘄𝗼𝗿𝗱 𝗮𝗻𝗱 𝘀𝗮𝘃𝗲 𝗹𝗶𝘃𝗲𝘀!

#CervicalCancerPrevention #HPV #CervicalScreening #WomensHealth #HealthAwareness #CancerAwareness #PreventCancer #Vaccination #EarlyDetection #SCABPharmacy

Autistic women are four times less likely to come in for smear tests in the UK.

I'm sorry if you don't have TikTok, but this is an emotional story of an autistic woman who was pushed into screening by a colleague, and had precancerous cells.

There are tips for easing the experience in the video.

Please go.

#cervicalcancer #CervicalScreening

https://vt.tiktok.com/ZSjmq5avH/

TikTok - Make Your Day

All booked in. Ending up walking around and sorting it face-to-mask. Only one other person in a mask. At a GP surgery. #GetTested #CervicalScreening #SmearTest
Council deletes trans-inclusive cervical screening tweet after vicious transphobic pile-on

A council was forced to delete a tweet encouraging trans men and non-binary people to attend cervical screenings after bigots blasted it.

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