Heliograph
postdoc in the School of Life Sciences, University of Warwick
previously, phd student @warwickphysics and postdoc @oxfordphysics
microbial motility, single molecules, microfluidics and coffee aficionado
Simone Coppola
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Matthias C. RilligHappy to share that my paper on creativity in research labs is out in the "Ten Simple Rules" article series.
Ten simple rules for fostering creativity in research labs
I hope you find it to be useful.
#creativity #research #science
https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1012788
Ten simple rules for fostering creativity in research labs
Research lab groups are hotspots for the education of the next generation of scientists, and making these units work as creatively as possible is essential for solving pressing issues in biology, the environment, and beyond. This article highlights 10 points that can help make labs as creative as possible. Several of these points are about setting up a creative lab culture; others are about fostering group-level creative output, some are more about encouraging creativity of individual team members, or both. While the head of a research group, the principal investigator, plays an important role, this can only be successful in healthy labs where everyone contributes.
Mary FesenkoI finally saw a majestic male mandarin duck at Golden Acre Park in Leeds today after being on the lookout of them for years! It may be an introduced species in the UK, but what a beauty it is!
Arrrgh I spent a while this afternoon crafting a paragraph of a discussion/perspectives section in my thesis and then, at the end, went back to one of my results figures to link it to my observations. This made me discover a *fatal flaw* in my hypothesis, so I had to delete the whole paragraph.
I was lured down this rabbit hole by my #CellBiology kryptonite: a paper about phosphoinositide signalling at lysosomes featuring awesome CLEM imaging 🤦♀️ #PhDeath #thesiswriting #academicchatter
Thanks for highlighting our preprint @focalplane_jcs: https://focalplane.biologists.com/2024/10/04/microscopy-preprints-applications-in-biology-10/
Microscopy is definitely a highlight of my work, especially getting to image my favourite cell organelles, that I had only seen in textbooks or other people’s papers prior to my PhD! I could watch endosomal tubules throwing shapes or vesicles zooming around all day, but usually have to keep acquiring images to get those ‘n’ numbers up!
The FocalPlane ‘how to’ posts are also a great source of technical tips! 🔬❤️
Omg I am loving today’s Google Doodle! Might order some Scoubisous string to make 3D depictions of the plasmids I made - the helical styles were my favourite to make in their 00s heyday 🧬 Will have to wait till I submit my thesis…don’t need any more ways to procrastinate now 😅
Happy to see my first-author preprint online 🎉 It’s been a fun challenge to find ways to distinguish different Intracellular Nanovesicle Identities in cells - ATG9-flavour INVs are only the first we’ve characterised! It was exciting to show that INVs function on a degradative trafficking pathway - macroautophagy - and the ATG9A lipid-scrambling capacity of these vesicles may be important in other membrane-remodelling contexts 🤔 Lots still to explore!
From: @steveroyle
https://biologists.social/@steveroyle/113125133783436536
Stephen Royle (@[email protected])
We have a new preprint out! It's about the molecularly diverse world of Intracellular Nanovesicles (INVs). ATG9 vesicles are a subtype of intracellular nanovesicle https://www.biorxiv.org/content/10.1101/2024.09.12.612637v1 @MAFesenko @Moore_cell Peyton Ewbank @[email protected] @[email protected] #CellBiology #MembraneTraffic #Proteomics 1/n
Seeing these vesicles zooming around the cell + then darting over to the mitochondria within seconds after you add the drug to trap them there never gets old 🔬🤩 #CellBiology #microscopy #membranetraffic #BiologyIsBeautiful
From: @steveroyle
https://biologists.social/@steveroyle/113125154969359577
Stephen Royle (@[email protected])
Attached: 1 image We noticed a key autophagy protein ATG9A in our proteome and got curious about the relationship between the previously described ATG9 vesicles and INVs. Through in-cell vesicle capture assays, we showed that ATG9 vesicles make up one subtype of INVs. 3/n
Stephen RoyleWe have a new preprint out!
It's about the molecularly diverse world of Intracellular Nanovesicles (INVs).
ATG9 vesicles are a subtype of intracellular nanovesicle
https://www.biorxiv.org/content/10.1101/2024.09.12.612637v1
@MAFesenko @Moore_cell Peyton Ewbank
@roylelab @Warwick_CMCB
We noticed a key autophagy protein ATG9A in our proteome and got curious about the relationship between the previously described ATG9 vesicles and INVs. Through in-cell vesicle capture assays, we showed that ATG9 vesicles make up one subtype of INVs.
3/n