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bioinfo, evolution @ mdmlab.
CR CNRS
lab websitehttps://mdmlab.fr

#Biblio

đź“° Beyond bacterial paradigms: uncovering the functional significance and first biogenesis machinery of archaeal lipoproteins

Read more :
đź”— https://pubmed.ncbi.nlm.nih.gov/39372745/?utm_source=tt-rss&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1J__86CjOXsuvouUy2mn7xTHM9rEKm31YLuY60Cw4Y2Wg-9o08&fc=20240930045650&ff=20241007131035&v=2.18.0.post9+e462414

Beyond bacterial paradigms: uncovering the functional significance and first biogenesis machinery of archaeal lipoproteins - PubMed

Lipoproteins are major constituents of prokaryotic cell surfaces. In bacteria, lipoprotein attachment to membrane lipids is catalyzed by prolipoprotein diacylglyceryl transferase (Lgt). However, no Lgt homologs have been identified in archaea, suggesting the unique archaeal membrane lipids require d …

PubMed

Just out in @PLOSBiology : an essay on ancestral #immunity, to understand why some part of the eukaryotic and bacterial #immuneSystems are conserved, despite constant arms race to fight viruses and parasites. We explore the new avenues this observation opens.

with @audeber and Enzo Poirier.

https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002717

The immune modules conserved across the tree of life: Towards a definition of ancestral immunity

A subset of prokaryotic antiviral systems are conserved in eukaryotes and have crucial roles in immune pathways. This Essay introduces the concept of ancestral immunity, which refers to the set of immune modules (domains and proteins) conserved between prokaryotes and eukaryotes, discussing the topology of ancestral immunity and a putative evolutionary scenario for its existence.

Systematic identification of cargo-mobilizing genetic elements reveals new dimensions of eukaryotic diversity 

https://doi.org/10.1093/nar/gkae327

#genomics #microbiology

Systematic identification of cargo-mobilizing genetic elements reveals new dimensions of eukaryotic diversity

Abstract. Cargo-mobilizing mobile elements (CMEs) are genetic entities that faithfully transpose diverse protein coding sequences. Although common in bacte

OUP Academic

This is a really great overview of innate immunity concepts across organisms. A really fantastic conceptual read and one that I may add to my "required reading" list for training new students/lab members in concepts of innate immunity.

https://www.cell.com/immunity/fulltext/S1074-7613(24)00128-6

#Drosophila #Celegans #HostPathogen #Immunology #InnateImmunity

In bash, writing ${var?} instead of just ${var} or $var means if var isn't defined then bash will throw an error and _not_ execute your command, instead of expanding it to "" and carrying on.

mv file1 file2 $subdir # oops, I overwrote file2
mv file1 file2 ${subdir?} # error message instead of disaster

My favourite use of this is for example commands in documentation, with placeholders for the user to fill in. Then it's OK if a user accidentally copy-pastes it _without_ filling them in!

I'm preparing a talk on resources for French civil servants (now they will have to attend one presentation on #climate, one on #biodiversity, and one on resources as part of a mandatory continuing education) and I thought I would share the images I'll be using here, as I find some of them are quite nice.

So see below for some impressive visualizations on our #resource #consumption.
⬇️

1/N

#dataviz #environment #resources #infrastructure #fossilFuels #metals #landUse #ecology #cattle

**A Partager !! ** Journée Femmes en Math et Informatique le 21 mai, pour tous les étudiants et étudiantes, organisée par moi-même à l'Université Paris-Saclay avec mon labo le LISN et la GS Informatique

⏬⏬⏬

https://www.lisn.upsaclay.fr/evenements/journee-femmes-en-math-et-informatique/

Journée Femmes en Math et Informatique

LISN | Laboratoire Interdisciplinaire des Sciences du Numérique

Gaza: «Nous avons face à nous tous les signes avant-coureurs d’un génocide»

Pour #AmnestyInternational, qui publie mercredi 24 avril son rapport annuel, la guerre à #Gaza est emblématique d’un ordre mondial «au bord de la rupture». Entretien avec la chercheuse #BudourHassan, qui enquête pour l’ONG sur les exactions commises par Israël.

› https://www.mediapart.fr/journal/international/240424/gaza-nous-avons-face-nous-tous-les-signes-avant-coureurs-d-un-genocide

Gaza : « Nous avons face Ă  nous tous les signes avant-coureurs d’un gĂ©nocide »

Pour Amnesty International, qui publie mercredi 24 avril son rapport annuel, la guerre Ă  Gaza est emblĂ©matique d’un ordre mondial « au bord de la rupture Â». Entretien avec la chercheuse Budour Hassan, qui enquĂŞte pour l’ONG sur les exactions commises par IsraĂ«l.

Mediapart

Happy to share the latest manuscript from our lab, in which we propose that eukaryotes evolved from a genomic chimera of Asgard archaea and giant viruses.

https://www.biorxiv.org/content/10.1101/2024.04.22.590592v1

This is a controversial topic, but we believe we have strong evidence to suggest a critical viral role in eukaryogenesis.

#viruses #protists #eukaryotes #evolution #TreeOfLIfe #archaea

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Journée mondiale de la #Terre
📢La goélette @TaraOcean_ a récemment fait escale à @villemarseille, lors d'un week-end événement, à l'occasion des 10 ans du @Mucem.

Voir le reportage👉
https://www.youtube.com/watch?v=XBvvM-hwK4Y

Fondation Tara Océan : la recherche au plus proche de l'océan

YouTube