Mastodawn

Aled May 3, 2023

RT @DMCBrainHealth
The DMCBH is pleased to officially become an #OpenScience Institute! Through a partnership with @TheNeuro_MNI's Tanenbaum Open Science Institute (TOSI), we have adopted a set of Open Science principles for collaboration and sharing research findings.
🔗: https://www.centreforbrainhealth.ca/news/djavad-mowafaghian-centre-for-brain-health-becomes-an-open-science-institute/

Djavad Mowafaghian Centre for Brain Health becomes an Open Science Institute - Djavad Mowafaghian Centre for Brain Health | DMCBH

The Djavad Mowafaghian Centre for Brain Health (DMCBH) is pleased to officially become an Open Science Institute. Through a partnership with The Neuro’s

Djavad Mowafaghian Centre for Brain Health | DMCBH

Aled May 3, 2023

RT @thesgconline
📢#JobAlert🚨
@CQMED_Unicamp in Brazil is hiring two #postdocs to work on #drugdiscovery! If you have a background in #molecularbio or #cellbio, apply now!
#postdocposition #jobopportunities
https://www.thesgc.org/careers/campinas-unicamp/center-medicinal-chemistry-brazil-hiring-two-post-docs-work-drug-discovery

The Center for Medicinal Chemistry, in Brazil, is hiring two post-docs to work on drug discovery in reproductive biology

The Center for Medicinal Chemistry (CQMED) at the University of Campinas (São Paulo, Brazil) is offering two positions for post-doctoral researchers to work on drug discovery in reproductive biology and disease. This is part of the inaugural SGC initiative Women’s and Children’s Health Program, funded by the Bill & Melinda Gates Foundation. Position 1 - Human genetic fertility diseases The researcher will be part of a multidisciplinary team in Prof. Dr. Fabio Papes' lab (LGE/Institute of Biology and CQMED) at UNICAMP. This project aims to study human genetic diseases that affect fertility.

SGC

Aled May 2, 2023

RT @thesgconline
The @acceleration_c has received a record-breaking CFREF to advance the #discovery of new materials and molecules. SGC is glad to be part of this! A Self Driving Lab led by @CherylArrowsmi1 will serve @UofT and affiliated hospitals, like @UHN
Read more: https://bit.ly/41VBzrr

Structural Genomics Consortium to lead AI-assisted Drug Discovery Initiative within the University of Toronto’s Acceleration Consortium

The University of Toronto's Acceleration Consortium has received a record-breaking $200 million Canada First Research Excellence Fund (CFREF) to advance the discovery of new materials and molecules. This award marks the largest single federal research grant to a university in Canadian history. By bringing together partners from academia, government and industry, the drug discovery component of the consortium aims to reduce the time and cost of developing chemical probes (the first step in a drug discovery program).

SGC

Aled Apr 28, 2023

RT @mattschap
Still a few days to apply for CACHE Challenge #4! https://bit.ly/4264vxs. Predict 100 compounds for an immuno-oncology target with an inhibitor in the clinic. We will test them experimentally and cover most of the costs. @HalabelianLab solved 8GCY and will try too with your hits

Finding ligands targeting the TKB domain of CBLB | CACHE

Accelerating the impact of AI-driven Drug Discovery

Aled Apr 27, 2023

RT @XChemInc
DELs, a faster way to tap into the ubiquitin-proteasome system. In supporting @Relay_Tx and @thesgconline, our high-quality DEL data facilitated the discovery of a promising #smallmolecule engager for DCAF1. http://ow.ly/qNMq50NL2Vm

#DEL #drugdiscovery

Discovery of Nanomolar DCAF1 Small Molecule Ligands | X-Chem

DCAF1 is a substrate receptor of two distinct E3 ligases (CRL4DCAF1 and EDVP), plays a critical physiological role in protein...

X-Chem

Aled Apr 26, 2023

RT @eLife
None of the five antibodies for TRPA1 available on the market were working as intended, invalidating all of @Harvin_Der_Virk’s findings.

He tells the story of how he turned around his PhD, and his faith in science, in the latest #SparksOfChange. https://elifesciences.org/articles/87444?utm_source=twitter&utm_medium=social&utm_campaign=organic

Careers: Tales of the unexpected

A single event can completely change the direction of a career in science; four researchers share their stories.

eLife

Aled Apr 21, 2023

Commercial antibodies get a bad rap, but there are thousands and thousands of great renewable ones on the market. We’re finding them for you. @GenomeCanada @ontariogenomics @GenomeQuebec #Reproducibility #openscience #ALS #Alzheimers #TREATAD
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RT @thesgconline
The @TheNeuro_MNI / @thesgconline initiative @YCharOS1 is paving the way towards characterizing commercially available #antibodies for every human protein. Conforming to #o…
https://twitter.com/thesgconline/status/1649406873118863366

Structural Genomics Consortium (SGC) on Twitter

“The @TheNeuro_MNI / @thesgconline initiative @YCharOS1 is paving the way towards characterizing commercially available #antibodies for every human protein. Conforming to #openscience, they've partnered with 9 antibody manufacturers to assess >700 antibodies using KO cell lines.”

Twitter

Aled Apr 19, 2023

Wow. The AL East is the toughest division in all of sport. The worst team (which are the Red Sox - I love saying that) would be competitive in any other division. Go Jays!

Aled Apr 16, 2023

RT @abbycanucks
A leader on and off the ice 👏

Chase Wouters is your 2022/23 #AbbyCanucks "Man of the Year Award" winner!🏆

Chase will also be the team's nominee for the Yanick Dupre Memorial Award for @TheAHL Man of the Year! 🙌

Congratulations Chase! 🥳 https://twitter.com/i/web/status/1647344165276237825

X - Abbotsford Canucks on Twitter

“A leader on and off the ice 👏 Chase Wouters is your 2022/23 #AbbyCanucks "Man of the Year Award" winner!🏆 Chase will also be the team's nominee for the Yanick Dupre Memorial Award for @TheAHL Man of the Year! 🙌 Congratulations Chase! 🥳”

Twitter

Aled Apr 12, 2023

Sleeping with a whole bunch of chicks tonight. #FarmLife