Prophylactic and therapeutic efficacy of #monoclonal #antibodies against #H5N1 #influenza virus

#KNCVMCCB2026 comes to an end with an interesting talk by Danielle Vugts. She talked about the importance of #imaging during #DrugDevelopment on the example of PET imaging of #biologics.

https://link.springer.com/article/10.1186/s41181-024-00258-y
#DrugDiscovery #PETImaging #Radiolabeling #Antibodies #Nanoparticles #Chemistry

#KNCVMCCB2026 comes to an end with an interesting talk by Danielle Vugts. She talked about the importance of #imaging during #DrugDevelopment on the example of PET imaging of #biologics. link.springer.com/article/10.1... #DrugDiscovery #PETImaging #Radiolabeling #Antibodies #Nanoparticles #ChemSky
How to Design Antibodies

A step-by-step guide to making de novo binders.

Asimov Press
#Panzootic #H5 #influenza viruses acquired #resistance to human head interface #antibodies

Longitudinal #assessment of functional #antibodies to a novel #influenza virus strain across age groups

Population #immunity to clade 2.3.4.4b #H5N1 is dominated by anti-neuraminidase #antibodies

Researchers identified that specific cross-reactive #antibodies acquired from seasonal #influenza exposure or #vaccination target the conserved "stem" region of the avian influenza A (#H5N1 ) virus, providing a baseline level of protection against the disease.
#Virology #Immunology #sflorg
https://www.sflorg.com/2026/02/vir02102601.html
Building Immunity Against Avian Flu Risks

A team from UNIGE has shown that certain antibodies to seasonal flu can also target avian flu.

A newly discovered antibody clamps the base of the spike protein of COVID-19 and other SARS viruses. This antibody is effective against multiple variants of the virus; variants that were unaffected by the antibody were also less infectious.

Summary: https://scitechdaily.com/a-tiny-antibody-just-crushed-the-coronaviruss-secret-weak-spot/

Original paper: https://www.nature.com/articles/s41467-025-60250-1

#Science #Health #COVID19 #Antibodies #Vaccination

#Netherlands, Another four #cows with #antibodies against #H5N1 #birdflu on a dairy farm in Friesland, https://www.biojournaal.nl/article/9806843/nog-eens-vier-koeien-met-antistoffen-tegen-vogelgriep-op-melkveebedrijf-in-friesland/

Outgoing Minister of Agriculture Femke Wiersma reported this to the House of Representatives on Thursday during a debate on zoonoses and animal diseases, NOS reports.

Nog eens vier koeien met antistoffen tegen vogelgriep op melkveebedrijf in Friesland

Op een melkveehouderij in Noardeast-Fryslân zijn bij in totaal vijf koeien antistoffen tegen het vogelgriepvirus H5N1 aangetroffen, wat erop wijst dat de dieren eerder met het virus in…