Mingqing Cai 

190 Followers
341 Following
305 Posts
Engineer antibodies and proteins as therapeutics; love to explore biology from an evolutionary perspective; live another life beyond Earther.
BoysAllowed to experiment with my DNAs
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Werner's Nomenclature of Colours

A guidebook with swatches to help when describing the colours of things before colour photography - as used by Darwin on his expeditions

https://www.c82.net/werner/

Werner's Nomenclature of Colours

A recreation of the original 1821 color guidebook with new cross references, photographic examples, and posters designed by Nicholas Rougeux

In case anyone was following the recent Science paper about using Tartrazine for #tissueclearing, apparently there is at least one (competing) group that couldn't reproduce it and wrote a preprint about it:

Tartrazine cannot make live tissues transparent
https://doi.org/10.1101/2024.09.29.615648

Discussion on Pubpeer, including the Tartrazine paper's author's response:
https://pubpeer.com/publications/81314BB3706B3D6ADAD49F301B2FA5

#lightsheet #microscopy #tartrazine

We are almost there folks hang in there

2020 ▓▓▓▓▓▓▓▓▓▓▓▓▓░ 619.71%

Happy 6th Anniversary to Lockdown Day 😭

Academia has a travel problem.

Attending faraway conferences is ecologically unsustainable, and creates a huge barrier to entry for people who are disabled, have care duties, or lack resources, among others.

One piece of the solution is to create local satellites of major conferences. This idea has been successfully implemented in Paris for #NeurIPS for a few years, and I'm happy to have joined the advising committee of NeurIPS@Paris (Dec 4&5 this year)

Check it out: https://neuripsinparis.github.io/neurips2024paris/

4th and 5th of December Sorbonne Center for Artificial Intelligence (SCAI)

4th and 5th of December Sorbonne Center for Artificial Intelligence (SCAI)

You can narrow Mastodon search results by language using the special operator "language:" For example if you include the phrase language:fr then the results would just show posts in French.

There's a list of all Mastodon's language codes at:

➡️ https://fedi.tips/language-codes-used-by-mastodon

There are lots more search operators listed at:

➡️ https://fedi.tips/how-do-i-search-for-stuff-on-mastodon

#FediTips #Mastodon

Language codes used by Mastodon | Fedi.Tips – An Unofficial Guide to Mastodon and the Fediverse

An unofficial guide to using Mastodon and the Fediverse

Recently I worked on a project that intends to develop a 'next-generation' or 'best-in-class' therapeutics. Drugs available in this field fail in some aspects either low efficacy or high tox. What surprises me is in principle some of the ideas behind these drugs are 'too good to be true' even by outdated standards, but companies still put billions of dollars into developing them. I feel like we can better utilize the $$$.
Quantification issue: when we develop therapeutics especially antibodies to membrane targets, we desire to quantify the target density on the cell surface. In the old days, this was done by quant-beads/flow cytometry. Unfortunately, the standardization of detection antibodies against quant-beads is painful. Any progress in this field? Thanks.
Is there a set of standard biological symbols we can use in Microsoft Word/PowerPoint? Symbols like "two molecules interacting with each other", "molecule A inhibits molecule B", etc. Thanks.
What links aging and disease? A growing body of research says it's a faulty metabolism
https://medicalxpress.com/news/2024-08-links-aging-disease-body-faulty.html
What links aging and disease? A growing body of research says it's a faulty metabolism

Aging is a biological process that no one can avoid. Ideally, growing old should be a time to relax and enjoy the fruits of your labor. Aging also has a darker side, however, often linked to disease.

Medical Xpress

Welcome to the new users who have decided to give mastodon a try. Also thanks for choosing genomic social. I don't get anything out of this other than the satisfaction of providing a service and potentially an alternative to twitter. An alternative that doesn't have ads and doesn't try to manipulate you with an algorithm to farm your engagement.

Have fun, start following (this is how you kick start your feed), and be kind.