New trauma center cut gunshot travel time by 10 minutes, deaths fell 3.9%
For decades, Chicago's South Side neighborhoods have experienced high rates of firearm violence, making speedy access to expert trauma care a matter of life and death. A recent study in JAMA Surgery helps quantify the impact of critical care: the opening of the University of Chicago Medicine's Level 1 trauma center in 2018 was associated with a nearly 4% reduction in firearm mortality, thanks to faster and closer emergency treatment.
A protein may help revive exhausted T cells in cancer immunotherapy
Immunotherapy has been one of the most transformative treatments for cancer patients in recent decades, shifting the emphasis from the broad-spectrum approach of chemotherapy to prompting the immune system's boldest warriors—its T cells—to target only the infiltrating tumor.
Is information or motivation to blame for partisan beliefs?
Partisanship, whether you support a particular person, group, or cause, has long been known as a key factor in misinformed beliefs—from COVID-19 to Brexit. But how does partisanship drive bias and misinformation? Is it because people of different parties consume different media? Or are we motivated to be biased?
AI outperforms conventional diagnosis for certain types of heart attacks
Artificial intelligence (AI)-based ECG interpretation outperformed standard pathways for the detection of occlusive myocardial infarction (MI), according to a study presented at ESC Acute CardioVascular Care 2026, the annual congress of the Association for Acute CardioVascular Care (ACVC), a branch of the European Society of Cardiology (ESC).
FDA-approved compound promotes neuroprotective effects in Parkinson's disease
Northwestern Medicine scientists have discovered that an FDA-approved compound promotes neuroprotective effects in experimental models of Parkinson's disease. The compound, N-acetyl-L-leucine (NALL), simultaneously targets multiple molecular pathways in dopaminergic neurons impacted by Parkinson's disease, underscoring NALL's potential therapeutic benefit in treating the disease in humans, according to the authors of the study published in the Journal of Clinical Investigation.
Can the critters in your mouth cause or cure disease?
No matter how much you brush, floss and rinse, there's a zoo colonizing your teeth, gums and tongue.
Engineered liver scaffolds reveal how colorectal cancer hides and goes dormant
Colorectal liver metastases (CRLM), cancer that has spread from the colon or rectum to the liver, have a deadly reputation. Due to its pervasive spread, typical cancer treatments like chemotherapy and surgical resection often prove ineffective. For the few patients who benefit from treatment, 75% still experience recurrence within two years and have poor survival outcomes.
'Off the shelf' immunotherapy could get a lift from gene-edited natural killer cells
https://medicalxpress.com/news/2026-02-shelf-immunotherapy-gene-natural-killer.html
'Off the shelf' immunotherapy could get a lift from gene-edited natural killer cells
Since scientists first discovered that human immune cells could be modified to become cancer-fighting agents, they've been trying to engineer a cell that's effective against solid tumors, which account for the vast majority of cancer cases. In a key advance in meeting this "holy grail challenge" in the field of cancer cell therapy, a team of Yale scientists led by geneticist Sidi Chen has revealed how immune cells can be "boosted" to target and eradicate solid tumors.
