C.Apr 30

I have a serious conflict in my desires.

I really want to see a photograph [1] of Dipshit Donnie at his desk in the oval office, with one of those twisty metal wires and colourful wooden beads toy things you see on the floor in the waiting rooms of doctors and dentists in front of him.

But I don't want it generated with "AI". I still have my ethics and principles.

[1] Doctored, obviously. Or given his trajectory, maybe it's just a matter of waiting another two weeks.

#USPol #DipshitDonnie #MangoMussolini #Trump #infantile #senescent

Daniel Hoffmann 🌼Feb 9, 2025
Killing #senescent cells (damaged cells that don't die) rejuvenates mice spectacularly. Now a study with fast #ageing childhood cancer survivors tests this in humans. https://www.theguardian.com/science/2025/feb/08/anti-ageing-jabs-they-can-rejuvenate-mice-but-will-they-work-on-humans
Anti-ageing jabs – they can rejuvenate mice, but will they work on humans?

Senescent cells power the body’s ageing process, and scientists are developing treatments to annihilate them

The Guardian
Daniel Hoffmann 🌼Jan 2, 2025
Prolonged use of energy rich "Western" diet can (in mice) revive #senescent #liver cells to #cancer cells. https://www.nature.com/articles/d41586-024-04137-z
Paradoxical link between senescent cell state and liver cancer resolved

DNA damage caused by a high-fat diet can increase the risk of tumour formation in the liver.

Scientific FrontlineOct 27, 2023
#Senescent cells have been implicated in a variety of processes typically connected with #deterioration and #aging. Recent studies suggest that the short-term presence of senescent cells can actually be beneficial.
#Biology #sflorg
https://www.sflorg.com/2023/10/bio10272301.html
Senescent Cells Key to Axolotl Limb Regeneration

Senescent cells, often referred to as “zombie cells”, are no longer dividing but also not dying.

UnivGroJobs (By: Jako Jellema)Aug 20, 2023

#PhD student studying #pathological
#senescence

Salary:
€ 2.789 - € 3.536 #PhDposition

"We are looking for an enthusiastic and ambitious PhD candidate in the Laboratory of Cellular senescence and age-related pathologies, headed by Prof. Marco Demaria to work on a project studying the contribution of #senescent cells to inflammatory and #fibrotic chronic disease. "

Required : MSc in #Biology

Closing date: August 24 CET

#UMCGroningen #UMCG #Groningen
https://werkenbijumcg.nl/-/vacatures/phd-student-studying-pathological-senescence/10419-02s00088pp

PhD student studying pathological senescence | Werken bij UMC Groningen

We are looking for an enthusiastic and ambitious PhD candidate in the Laboratory of Cellular senescence and age-related…

Werkenbijumcg.nl
PLOS BiologyMay 31, 2023
#TissueDamage induces spatially distinct patterns of #senescent & #proliferative cell behaviors; this allocates distinct cellular tasks required for tissue repair, driven by mutual repression between JNK/AP-1 & JAK/STAT signaling @classenlab #PLOSBiology https://plos.io/43dDU1z
Mutual repression between JNK/AP-1 and JAK/STAT stratifies senescent and proliferative cell behaviors during tissue regeneration

This study shows that tissue damage induces spatially distinct patterns of senescent and proliferative cell behaviors; this spatial separation allocates distinct cellular tasks that are required for tissue repair and is driven by mutual repression between JNK/AP-1 and JAK/STAT signaling.

Justin D Kruger (he/him)Apr 17, 2023

Benefits of 'zombie' cells: Senescent cells aid regeneration in salamanders.

https://phys.org/news/2023-04-benefits-zombie-cells-senescent-aid.html
#news #senescent #longevity #aging

Benefits of 'zombie' cells: Senescent cells aid regeneration in salamanders

Senescent cells, often referred to as "zombie" cells, have long been associated with aging and disease. However, a new study from the Center for Regenerative Therapies Dresden (CRTD) at TU Dresden adds to a growing body of evidence that not all senescent cells are harmful.

CellBioNewsApr 15, 2023

Benefits of 'zombie' cells: #Senescent #cells aid #regeneration in #salamanders.

https://phys.org/news/2023-04-benefits-zombie-cells-senescent-aid.html

Benefits of 'zombie' cells: Senescent cells aid regeneration in salamanders

Senescent cells, often referred to as "zombie" cells, have long been associated with aging and disease. However, a new study from the Center for Regenerative Therapies Dresden (CRTD) at TU Dresden adds to a growing body of evidence that not all senescent cells are harmful.

Scientific FrontlineApr 14, 2023
#Scientists show that so-called #senescent #cells, i.e., cells that have permanently stopped dividing, boost production of new #muscle cells to enhance regeneration of lost limbs in #salamanders. (#Zombie cells)
#Biology #sflorg
https://www.sflorg.com/2023/04/bio04142301.html
Benefits of “Zombie” Cells: Senescent Cells Aid Regeneration in Salamanders

Senescent cells, often referred to as "zombie" cells

CellBioNewsApr 3, 2023

From yeast to mice, from mice to man: #Senescent #cells get noisier with #age.

#transcription

https://phys.org/news/2023-04-yeast-mice-senescent-cells-noisier.html

From yeast to mice, from mice to man: Senescent cells get noisier with age

Getting old seems completely avoidable in youth but becomes less and less so as we age. Many of the obstacles of advanced aging are well understood, including declining eyesight, hearing loss, back, neck and arthritic joint pains, shortness of breath, diabetes, Alzheimer's disease, dementia, cancer and stroke, just to name a few. What is less understood are the cellular-level molecular mechanisms responsible for our overall decline.

Phys.org