Our final
#JSE 2024🏆Outstanding Paper Award feature is a fascinating journey into the world of
#cryptic lineages and potential introgression in a mixed-
#ploidy species (
#Phragmites australis) across temperate
#China.
https://onlinelibrary.wiley.com/doi/10.1111/jse.12672Wiley Plant Science
#systematics #evolution #botanyIncreasing
#AntimicrobialResistance is of great medical concern. This Primer highlights a
@PLOSBiology study that unveils the link between
#ploidy plasticity and the emergence of
#antifungal resistance in
#Candida tropicalis. Paper:
https://plos.io/3RAckqM Primer:
https://plos.io/4i4sgN4
An agricultural triazole induces genomic instability and haploid cell formation in the human fungal pathogen Candida tropicalis
Candida tropicalis is a important human pathogen that is increasingly resistant to azole antifungals. Although C. tropicalis was thought to be strictly diploid, this study shows that a widely used agricultural fungicide induces ploidy plasticity, leading to the formation of haploid cells that are cross-resistant to antifungal drugs.
Any others working with mixed ploidy species or populations might be interested in this new paper and #rstats package 📦 🧬
#genomics #bioinformatics #ploidy
https://bsapubs.onlinelibrary.wiley.com/doi/full/10.1002/aps3.11606
Ploidy varies within and between fungal species. @HittingerLab reveal how strong conditional selection on a metabolic trait can lead to
#ploidy & cell type evolution in the wild
#yeast #Saccharomyces eubayanus
#PLOSBiology https://plos.io/3QwtFQE
Ploidy evolution in a wild yeast is linked to an interaction between cell type and metabolism
Ploidy is a fundamental trait of all organisms, but it varies within and between fungal species. This study reveals how strong conditional selection on a metabolic trait can lead to ploidy and cell type evolution in the wild yeast Saccharomyces eubayanus.
Leishmania genetic exchange is mediated by IgM natural antibodies - Nature
Genetic exchange of Leishmania parasites in the sand fly host is mediated by natural IgM antibodies, providing insights that will help generate reproducible and increased recovery of backcrosses for research purposes.
How do #yeast adapt to #chromatinization with human #histones and subsequent #aneuploidy?
Jeff Boeke, @maxhaase et al from NYU Langone find #ploidy stabilization by DASH/Dam1 complex mutants that weaken #kinetochore-#microtubule attachment strength
https://www.embopress.org/doi/10.15252/embj.2022112600
Paper out: Is there
#hybridisation across
#ploidy levels in
#parasitic eyebrights? Thanks to @alex_twyford and @Euphrasiologist for letting me do the demographic modelling
https://doi.org/10.1002/ajb2.16100 🌱🧬
J of Systematics and Evolution
PLOS Biology
Luke Pembleton
Tim Downing
The EMBO Journal
Hannes Becher