Fent uns electuaris (tipo cagalló de cabra, que els dic jo), per la meva gossa que té leishmaniasis i quan arriba la calor està una mica més tova perquè la leishmània revifa.

Aquests porten:
👉🏻 1 part de bisglicinat de magnesi
👉🏻 1 part de picolinat de zinc
👉🏻 2 parts d'Schyzophyllum commune
👉🏻 2 parts de Ganoderma lucidum
👉🏻 2 parts de fulla d'olivera
👉🏻 4 parts d'spirulina
👉🏻 4 parts d'artemisinina

La mel serveix d'aglutinant i aporta probiòtics.

Els electuaris son remeis coneguts des d'antic al Mediterrani. I és un dels molts que ensenyo a fer al curs de Remeieria tradicional Mediterrània. Les inscripcions ja estan obertes.
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#remeisnaturals #remeistradicionals #mel #electuari #herbesremeieres #herbesmedicinals #plantesmedicinals #plantesremeieres #fitoterapia #salutnatural #Leishmaniasis #leishmania #artemisinin #fitoterapiaveterinaria #veterinarianatural

https://journals.plos.org/plosntds/article?id=10.1371%2Fjournal.pntd.0012028 Challenges for maintaining post elimination phase of visceral leishmaniasis control programme in India: A field-based study #MedMastodon #India #KalaAzar #Leishmania "8 more PKDL cases (1 in ‘Study’ and 7 in ‘Control’ arm) were diagnosed during 4th survey"
Challenges for maintaining post elimination phase of visceral leishmaniasis control programme in India: A field-based study

Author summary The present study was conducted in a kala-azar endemic block of Malda district, West Bengal. The study areas were divided ‘Study’ and ‘Control’ arm and three active mass surveys were conducted for detection of visceral leishmaniasis (VL), post kala-azar dermal leishmaniasis (PKDL) and asymptomatic leishmanial infection (ALI). In the ‘Study’ arm, diagnosed ALI cases were treated with Liposomal Amphotericin B. No significant difference was noted between the incidence of VL and PKDL cases in ‘Study’ and ‘Control’ arm. But the incidence of ALI cases declined sharply in ‘Study’ arm and increasing trend was observed in ‘Control’ arm. A significantly higher rate of sero-conversion was noted in ‘Control’ arm. In both ‘Study’ and ‘Control’ arm, the sero-conversion rate was significantly associated with untreated ALI burden. Persistence of significant number of PKDL and ALI and ongoing transmission as evidenced by new infection and detection of leishmanial DNA in sand-flies may jeopardise the maintenance of post-elimination phase. Therefore, constant vigilance is highly needed to prevent resurgence of VL epidemic. Detection and long-term follow-up of ALI may also help to sustain the elimination. However, feasibility and cost-effectiveness study for detection and treatment of ALI should also receive attention.

A Disfiguring Parasite From Sand Flies Is Endemic In The U.S.

The Leishmania found in Texas and OK causes the mildest form, cutaneous leishmania, affecting only the skin. Will more serious leishmania strains become established, too?

Forbes
Leishmania genetic exchange is mediated by IgM natural antibodies - Nature

Genetic exchange of Leishmania parasites in the sand fly host is mediated by natural IgM antibodies, providing insights that will help generate reproducible and increased recovery of backcrosses for research purposes.

Nature

HOP1 and HAP2 are conserved components of the meiosis-related machinery required for successful #mating in #Leishmania

https://www.researchsquare.com/article/rs-3054842/v1

#meiosis #leishmaniasis #genome #genomics #mitosis #sexual #parasexual #fusion #cellfusion

HOP1 and HAP2 are conserved components of the meiosis-related machinery required for successful mating in Leishmania

Sexual recombination in Leishmania during development in the sand fly vector has been implicated based on Mendelian parental contributions observed in experimental hybrid genomes. Here, we performed functional analyses using in vitro and in vivo hybridization protoco...

#Aneuploidies are an ancestral feature of #trypanosomatids, and an ancient chromosome #duplication is maintained in extant species

João Luís Reis-Cunha et al
bioRxiv 2023.06.26.546280; doi: https://doi.org/10.1101/2023.06.26.546280

#leishmania #genome #genomics #aneuploidy

"Here, we tested the ability of the #leishmania major sphingolipids inositol phosphorylceramide (IPC), and ceramide to shelter ergosterol by preventing binding and cytotoxicity of the sterol-specific toxins streptolysin O and perfringolysin O using flow cytometry. In contrast to mammalian systems, Leishmania sphingolipids did not preclude toxin binding to sterols in the membrane. However, IPC interfered with cytotoxicity."

#Preprint

https://www.biorxiv.org/content/10.1101/2022.06.15.496300v3#review

Hello! Here's my #introduction I'm a Professor of #Parasitology in the UK working on the skin disease cutaneous #leishmaniasis. I have two heads - I work on the biology of #Leishmania parasites and also working with anthropologists to learn more about #stigma and wider effects (beyond pathology) on people with the disease #Twittermigration