Mastodawn

Final version published in Nature Reviews Earth and Environment:

Constraining the effect of global change on antifungal resistance

#antifungal #pesticides #environment #soil

https://www.nature.com/articles/s43017-025-00756-w

Constraining the effect of global change on antifungal resistance - Nature Reviews Earth & Environment

Antifungal resistance is a growing crisis affecting human health and agriculture that could be accelerated by global change. We call for a One Health research agenda to systematically investigate environmental drivers and inform policy to mitigate the potential of global environmental change in fuelling antifungal resistance.

Nature

JIPB Jan 22

🍅It's #TomatoTuesday on Thursday!
🍅This time,🍅we join🍅Chen et al. as they investigate the #biosynthesis, regulation, and metabolic #engineering of #antifungal, #antibacterial,🍅and #anticancer compounds in #tomato.🍅
🍅 https://doi.org/10.1111/jipb.70077
@WileyLifeSci
#PlantSci #botany

Dave Muth Jan 16

RE: https://mastodon.social/@ScienceScholar/115900165282256485

This is encouraging news. Fungi have been kicking our butts for a while, now.
#PublicHealth #Medicine #AntiFungal

VTC News Bot Jan 14

Bộ Y tế đình chỉ và thu hồi 8 sản phẩm mỹ phẩm chứa chất kháng nấm do không đảm bảo an toàn. Người tiêu dùng được khuyến cáo ngừng sử dụng ngay các sản phẩm này. #MyPham #ThuHoiMyPham #BoYTe #ChongNam #Health #CosmeticRecall #Antifungal #Vietnam

https://vtcnews.vn/8-my-pham-bi-bo-y-te-thu-hoi-co-dau-goi-nhap-khau-gia-toi-500-000-dong-ar998451.html

8 mỹ phẩm chứa chất kháng nấm bị Bộ Y tế thu hồi, yêu cầu ngừng sử dụng

Cục Quản lý dược (Bộ Y tế) vừa quyết định đình chỉ lưu hành và thu hồi trên toàn quốc 8 sản phẩm mỹ phẩm chứa hoạt chất kháng nấm.

Báo điện tử VTC News

JIPB Jun 16, 2025

Let's play "Supervillain or #antifungal lipopeptides?"
Yuan et al. will go first...
...with a new study, showing that iturin and fengycin lipopeptides inhibit #pathogenic #Fusarium in #wheat, targeting components of the #cell membrane and more!
https://doi.org/10.1111/jipb.13933
@wileyplantsci
#PlantSci #JIPB #botany

PLOS Biology Apr 22, 2025

Coccidioides is a fungal #pathogen that forms a unique structure, the spherule. This transcriptomic study of #Coccidioides development reveals spherule-specific gene regulation, Ryp1-dependent virulence factors, and potential #antifungal therapeutic targets @PLOSBiology https://plos.io/4cINMpl

Transcriptomic atlas throughout Coccidioides development reveals key phase-enriched transcripts of this important fungal pathogen

Coccidioides is a neglected fungal pathogen that forms a unique structure, the spherule, to cause disease. This study provides the first high-density transcriptomic analysis of Coccidioides development, showing spherule-specific gene regulation, Ryp1-dependent virulence factors, and potential targets of antifungal therapy.

PLOS Biology Apr 3, 2025

Increasing #AntimicrobialResistance is of great medical concern. This Primer highlights a @PLOSBiology study that unveils the link between #ploidy plasticity and the emergence of #antifungal resistance in #Candida tropicalis. Paper: https://plos.io/3RAckqM Primer: https://plos.io/4i4sgN4

An agricultural triazole induces genomic instability and haploid cell formation in the human fungal pathogen Candida tropicalis

Candida tropicalis is a important human pathogen that is increasingly resistant to azole antifungals. Although C. tropicalis was thought to be strictly diploid, this study shows that a widely used agricultural fungicide induces ploidy plasticity, leading to the formation of haploid cells that are cross-resistant to antifungal drugs.

Kai Kupferschmidt Mar 20, 2025

Multidrug-resistant bacteria get lots of attention. But some #fungi, too, have become immune to almost every known treatment available, posing another critical threat to global health. Now, researchers have found a compound that seems to kill fungi in an entirely new way: mandimycin.
„A new #antifungal is always exciting and very welcome,” says Oliver Cornely.

https://www.science.org/content/article/deadly-fungi-are-becoming-drug-resistant-new-compound-could-beat-them

Bill Loguidice Oct 28, 2024

New research shows effects of antimicrobial exposure on the risk of Parkinson's disease #parkinsons #research #antifungal #brain #pd #study

https://fullsteamahead365.com/2024/10/28/new-research-shows-effects-of-antimicrobial-exposure-on-the-risk-of-parkinsons-disease/

New research shows effects of antimicrobial exposure on the risk of Parkinson's disease - fullSTEAMahead365

Researchers used a nested case-control study design to evaluate the impact of antimicrobial exposure on the risk of developing Parkinson's disease (PD), a movement disorder that manifests as tremors, stiffness, and balance issues.

fullSTEAMahead365

Jason Yip Oct 22, 2024

#Antifungal resistance is not getting nearly as much attention as antibiotic resistance – yet the risks to global health are just as serious https://theconversation.com/antifungal-resistance-is-not-getting-nearly-as-much-attention-as-antibiotic-resistance-yet-the-risks-to-global-health-are-just-as-serious-239677

Antifungal resistance is not getting nearly as much attention as antibiotic resistance – yet the risks to global health are just as serious

And, as with antibiotics, their widespread use in agriculture is serious problem.

The Conversation