Systemic candidiasis is a severe, opportunistic #fungal infection caused by Candida albicans. Recent research demonstrates that reprogramming the metabolic pathways of a host's immune cells offers a viable strategy to clear the infection, circumventing the need for traditional #antifungal medications.
#Immunology #Microbiology #sflorg
https://www.sflorg.com/2026/04/imgy04032601.html
Study Points Toward Immune Reprogramming to Treat Candidiasis

Systemic candidiasis is an opportunistic fungal infection that has been difficult to treat effectively

Final version published in Nature Reviews Earth and Environment:

Constraining the effect of global change on antifungal resistance

#antifungal #pesticides #environment #soil

https://www.nature.com/articles/s43017-025-00756-w

Constraining the effect of global change on antifungal resistance - Nature Reviews Earth & Environment

Antifungal resistance is a growing crisis affecting human health and agriculture that could be accelerated by global change. We call for a One Health research agenda to systematically investigate environmental drivers and inform policy to mitigate the potential of global environmental change in fuelling antifungal resistance.

Nature
🍅It's #TomatoTuesday on Thursday!
🍅This time,🍅we join🍅Chen et al. as they investigate the #biosynthesis, regulation, and metabolic #engineering of #antifungal, #antibacterial,🍅and #anticancer compounds in #tomato.🍅
🍅 https://doi.org/10.1111/jipb.70077
@WileyLifeSci
#PlantSci #botany

RE: https://mastodon.social/@ScienceScholar/115900165282256485

This is encouraging news. Fungi have been kicking our butts for a while, now.
#PublicHealth #Medicine #AntiFungal

Bộ Y tế đình chỉ và thu hồi 8 sản phẩm mỹ phẩm chứa chất kháng nấm do không đảm bảo an toàn. Người tiêu dùng được khuyến cáo ngừng sử dụng ngay các sản phẩm này. #MyPham #ThuHoiMyPham #BoYTe #ChongNam #Health #CosmeticRecall #Antifungal #Vietnam

https://vtcnews.vn/8-my-pham-bi-bo-y-te-thu-hoi-co-dau-goi-nhap-khau-gia-toi-500-000-dong-ar998451.html

8 mỹ phẩm chứa chất kháng nấm bị Bộ Y tế thu hồi, yêu cầu ngừng sử dụng

Cục Quản lý dược (Bộ Y tế) vừa quyết định đình chỉ lưu hành và thu hồi trên toàn quốc 8 sản phẩm mỹ phẩm chứa hoạt chất kháng nấm.

Báo điện tử VTC News
Let's play "Supervillain or #antifungal lipopeptides?"
Yuan et al. will go first...
...with a new study, showing that iturin and fengycin lipopeptides inhibit #pathogenic #Fusarium in #wheat, targeting components of the #cell membrane and more!
https://doi.org/10.1111/jipb.13933
@wileyplantsci
#PlantSci #JIPB #botany
Coccidioides is a fungal #pathogen that forms a unique structure, the spherule. This transcriptomic study of #Coccidioides development reveals spherule-specific gene regulation, Ryp1-dependent virulence factors, and potential #antifungal therapeutic targets @PLOSBiology https://plos.io/4cINMpl
Transcriptomic atlas throughout Coccidioides development reveals key phase-enriched transcripts of this important fungal pathogen

Coccidioides is a neglected fungal pathogen that forms a unique structure, the spherule, to cause disease. This study provides the first high-density transcriptomic analysis of Coccidioides development, showing spherule-specific gene regulation, Ryp1-dependent virulence factors, and potential targets of antifungal therapy.

Increasing #AntimicrobialResistance is of great medical concern. This Primer highlights a @PLOSBiology study that unveils the link between #ploidy plasticity and the emergence of #antifungal resistance in #Candida tropicalis. Paper: https://plos.io/3RAckqM Primer: https://plos.io/4i4sgN4
An agricultural triazole induces genomic instability and haploid cell formation in the human fungal pathogen Candida tropicalis

Candida tropicalis is a important human pathogen that is increasingly resistant to azole antifungals. Although C. tropicalis was thought to be strictly diploid, this study shows that a widely used agricultural fungicide induces ploidy plasticity, leading to the formation of haploid cells that are cross-resistant to antifungal drugs.

Multidrug-resistant bacteria get lots of attention. But some #fungi, too, have become immune to almost every known treatment available, posing another critical threat to global health. Now, researchers have found a compound that seems to kill fungi in an entirely new way: mandimycin.
„A new #antifungal is always exciting and very welcome,” says Oliver Cornely.

https://www.science.org/content/article/deadly-fungi-are-becoming-drug-resistant-new-compound-could-beat-them

New research shows effects of antimicrobial exposure on the risk of Parkinson's disease - fullSTEAMahead365

Researchers used a nested case-control study design to evaluate the impact of antimicrobial exposure on the risk of developing Parkinson's disease (PD), a movement disorder that manifests as tremors, stiffness, and balance issues.

fullSTEAMahead365