Karthik Srinivasan (@[email protected])

Attached: 1 image @PessoaBrain @NicoleCRust @[email protected] @[email protected] How far back? Really far back. Here's one fundamental example. Did Hebb come up with what we now call Hebb's Law? Hebb himself said otherwise. Find below a letter from Hebb (1977) acknowledging Eugenio Tanzi of having postulated it earlier in 1893!! #neuroscience #history #OldNeuroPapers

Neuromatch Social

@DrYohanJohn

#JohnBickle #neurohistory lecture:

#compneuro limits

A Hodgkin & A Huxley
1952s
Papers quartet duo written
—with one B Katz trio

Pioneering voltage-clamp squid neural implant.

First action potentials recordings!

Last paper on how maths calculus derived from experiments datasets.

Thus predictions caveat:
Never link causal mechanisms.

ps: Q&A critical feedback:
Skilled lecturer turns into scientific dialogues!

https://www.youtube.com/watch?v=g85bgHul7Ns

#oldneuropapers
#neuroscience
#neurobuzz

Computational Modeling Limits In Neuroscience – John Bickle, Ph.D.

YouTube

The idea that ephaptic coupling is involved in neuronal synchrony was put forward back in 1970 by N. Yu. Belenkov, "Ephaptic Transmission of Excitation as a Factor in the Synchronization of Neuronal Activity", published in the book "Electrophysiology of the Central Nervous System" 978-0306303814

#OldNeuroPapers

(idk why he says the etymology of ephaptic means "to set on fire," it's epi- hapto-, as in haptic https://en.wiktionary.org/wiki/%E1%BC%90%CF%86%CE%AC%CF%80%CF%84%CF%89#Ancient_Greek )

ἐφάπτω - Wiktionary, the free dictionary

@kordinglab

apropos of NMDARs Glutamate:

fav top notch most impressive #scihistory #neurolecture ever!

"Unnoticed Features of Exploratory Experiments from the 60-Year History of the N-methyl - D-aspartate (NMDA) Receptor"
https://youtu.be/xrNrLcE2RZE
John Bickle
2023

From 1949 Hebb
'in one or both cells'
then Watkins, Morris, Collingridge, etc. to
2023 #PhilSci Haueis

#neurophysiology
#neurohistory
#neurodon
#neuroscience
#oldneuropapers
#cogsci
#neurobuzz
#systemsneuroscience
#complexsystems

John Bickle: Unnoticed Features of Exploratory Experiments..."

YouTube

Hi everyone! here is our annual call for #PhD #students

Please #boost !!

https://www.unife.it/studenti/dottorato/en/concorsi-en/concorso-per-titoli-e-colloquio-per-laccesso-al-39deg-ciclo

We are a happy bunch of engineers, biologists, psychologists and medical doctors trying to make sense of the #neurophysiology of action-perception coupling during solo (boring) and interactive (fun!) tasks.

We do a lot of #brainstimulation , #electroencephalography , #motioncapture , etc

We're also a weird bunch, because we love the #history of ideas, #OldNeuroPapers and many other unrelated things :))

Here are some recent representative publications:

https://pubmed.ncbi.nlm.nih.gov/36327142/
https://pubmed.ncbi.nlm.nih.gov/36328272/
https://pubmed.ncbi.nlm.nih.gov/35372806/
https://pubmed.ncbi.nlm.nih.gov/34433079/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7598921/

#neuroscience #academicjobs

Call for applications based on qualifications and interview for the admission to the 39th Cycle — Research Doctorates

"The velocity of thought"

Directly from 1870, a true gem from the past.

M. Foster writes about recent explorations moving from the quantification of 'physiological time' or nerve conduction speed (Helmholtz) to the 'speed of thought', which, using the subtractive method, allowed Donders to open up a whole new world to us.

https://www.nature.com/articles/002002a0

*The description of the technique used to measure the short intervals between electrical stimulation of nerves and muscle activity gives a measure of the epic nature of science at that time.

For a little more context:
https://pubmed.ncbi.nlm.nih.gov/12535921/

*The conclusions (screenshots below) could be written today:
- We need standardisation of the tool/instruments
- We need large samples to draw accurate inferences

#neuroscience #psychology #cognition #history #OldNeuroPapers
#replicability

The Velocity of Thought - Nature

“AS quick as thought” is a common proverb, and probably not a few persons feel inclined to regard the speed of mental operations as beyond our powers of measurement. Apart, however, from those minds which take their owners so long in making up because they are so great, rough experience clearly shows that ordinary thinking does take time; and as soon as mental processes were brought to work in connection with delicate instruments and exact calculations, it became obvious that the time they consumed was a matter for serious consideration. A well-known instance of this is the “personal equation” of the astronomers. When a person watching the movement of a star, makes a signal the instant he sees it, or the instant it seems to him to cross a certain line, it is found that a definite fraction of a second always elapses between the actual falling of the image of the star on the observer's eye, and the making of the signal—a fraction, moreover, varying somewhat with different observers, and with the same observer under differing mental conditions. Of late years considerable progress has been made towards an accurate knowledge of this mental time.

Nature

@nadel

add some tags —even easily by editing after posting— to improve such kind of cool posts, ie:

#neurohistory
#neurodon
#neuroscience
#oldneuropapers

cc
@NicoleCRust for aditional tag suggestions!

@LeonDLotter The ML community started using #PaperThread - @NicoleCRust set up #oldneuropapers to highlight fundamental neuro work and one could do #newneuropapers for new publications to keep it consistent. I feel it’s generally been a bit quite here over the holidays but I am sure the #neuroscience community will start sharing their new work again more actively soon!
@PessoaBrain @TEG. Thanks! 1980s. Since we already decided that's not old, at least for some of us (in terms of the #OldNeuroPapers initiative), let's call that newish.

@NicoleCRust @TEG

There were some versions of basal ganglia loops involving emotion/motivation in the mid 1980s.

The famous paper is of course this one, which led all textbooks to talk about a "limbic loop" (but please avoid this term!).

I never had the chance to track it further back, but it would be a beautiful project! 🙂

Also: current understanding of basal ganglia loops have evolved from the idea of segregated loops, although some still like this notion.

#neuroscience
#history
#OldNeuroPapers