Brain and Endocrine Crosstalk
by Hemanshu Prabhakar, 2026
This book explores the physiology and neurophysiology of the endocrine system, emphasizing the intricate brain-endocrine crosstalk, from pathophysiology to clinical applications. The dynamic interplay between neural and endocrine system regulates nearly every function of human body, from metabolism and growth to circadian rhythm.
#books
#nonfiction
#medical
#brain
#endocrine
#physiology
#NeuroPhysiology
Just out on @thetransmitter: 18 teams analyzed the same #Neuropixels dataset and obtained strongly divergent answers.
Even for #SharpWaveRipple detection, the apparent consensus masked major differences: Some teams detected almost no ripples, others up to 10 per minute. Functional connectivity and spike-spike interaction analyses diverged even more.
#Neuroscience #CompNeuro #electrophysiology #Neurophysiology
A rat study has found that moderate aerobic exercise leads to remodeling of stellate ganglia in the neck and upper chest--part of the autonomic nervous system that regulates heart activity. Ganglia on left and right sides of the body underwent different changes in number, size, and volume.
Summary: https://scitechdaily.com/exercise-changes-the-heart-in-a-way-researchers-never-expected/
Original paper (not open access): https://www.autonomicneuroscience.com/article/S1566-0702(25)00100-6/abstract
#Science #Neurophysiology #Neuroplasticity #Heart #Exercise #Aerobics
This brief highlights a link between everyday physical activity and brain housekeeping processes, offering a timely reminder of how motor activity can intersect with cognitive well-being. For clinicians across disciplines, the finding underscores how even minimal muscle engagement may support neural clearance mechanisms, which can inform holistic approaches to mental health maintenance and stress-related symptom management. The content invites consideration of movement-based strategies as supplementary, non-pharmacological factors in promoting brain function, without implying clinical prescriptions.
Article Title: Scientists discover a hidden brain “cleaning” effect triggered by movement
Link to Science Daily Mind-Brain News: https://nolinkpreview.com/www.sciencedaily.com/releases/2026/05/260501052832.htm
#neuroscience
#brainhealth
#movementandmind
#mentalhealthresearch
#cerebrospinalfluid
#neurophysiology
#psychotherapyresearch
#wellbeing
#somaticpractice
Research Technician (Drosophila Neurobiology)
Indiana University Bloomington
See the full job description on jobRxiv: https://jobrxiv.org/job/indiana-university-bloomington-27778-research-technician-drosophila-neurobiology/
#behavioralneuroscience #drosophila #neurobiology #neurophysiology #ScienceJobs #hiring #research
https://jobrxiv.org/job/indiana-university-bloomington-27778-research-technician-drosophila-neurobiology/?fsp_sid=10681
Oxytocin is a neuropeptide that can promote or inhibit affiliative social behaviors. Recent evidence suggests that these diverse effects are mediated by distinct oxytocin receptor-expressing neurons. An outstanding question is whether these behavioral effects are also driven by distinct or overlapping populations of oxytocin-producing neurons. The paraventricular nucleus (PVN) of the hypothalamus is a major source of oxytocin and sends projections to the mesolimbic dopamine system and extended amygdala. Previous work found that social defeat stress increased oxytocin neuron activity in the anterior PVN (aPVN) but not posterior PVN (pPVN). We reduced oxytocin synthesis with antisense morpholino oligonucleotides in either anterior or posterior PVN in California mice (Peromyscus californicus), a strong model system for studying effects of social stress on brain function and behavior. Antisense morpholinos in aPVN had no effect on behavior in unstressed females but increased social approach and reduced social vigilance in females exposed to social defeat stress. In pPVN, antisense morpholinos reduced social approach in unstressed male and female California mice. We then used OxtCre mice to compare electrophysiological profiles of oxytocin in aPVN and pPVN with a population of oxytocin neurons in the bed nucleus of the stria terminalis (BNST). Oxytocin neurons in aPVN and BNST had higher post-synaptic events and responded more strongly to current injections than oxytocin neurons in pPVN, though they had similar excitatory and inhibitory input balance at the observed resting membrane potential. These findings shed light on to functional and physiological heterogeneity of PVN oxytocin neurons. Our results suggest that context-dependent behavioral effects of oxytocin are mediated by different populations of oxytocin neurons.
A giant and master of neurophysiology left us. Farewell prof. Hallett #neuroscience #neurophysiology
In Memoriam Professor Mark Hallett, MD (1943–2025)
https://wfneurology.org/activities/news-events/wfn-news/2025-11-05-wfn-mark-hallett
earthling
Francis Mangion (M)
Fabrizio Musacchio
RDN
Scientific Frontline
Psychotherapy Commission ACPE
jobRxiv
CD Castillo
Lucio Marinelli