@DhananjayThakur

You might also enjoy this #neurolecture recalling #hodgkinhuxley #neurohistory seminal quintet of papers, remarking how became aware of their model limitations, written in the 1952 d/4th paper:

Forgotten lesson in nowadays #compneuro models research!

» wetlab interventionist experimentation must remain the principal activity in the search for neurobiological mechanisms, for the same reasons Hodgkin & Huxley realized nearly 70 years ago «

#JohnBickle

https://youtu.be/g85bgHul7Ns

@DrYohanJohn

#JohnBickle #neurohistory lecture:

#compneuro limits

A Hodgkin & A Huxley
1952s
Papers quartet duo written
—with one B Katz trio

Pioneering voltage-clamp squid neural implant.

First action potentials recordings!

Last paper on how maths calculus derived from experiments datasets.

Thus predictions caveat:
Never link causal mechanisms.

ps: Q&A critical feedback:
Skilled lecturer turns into scientific dialogues!

https://www.youtube.com/watch?v=g85bgHul7Ns

#oldneuropapers
#neuroscience
#neurobuzz