hmmmm, the "exlusome"
#structbio #molecularcell #Science
From: @bioRxiv_cellbiol
https://botsin.space/@bioRxiv_cellbiol/109956833473897972
📰 "A special envelope separates extra-chromosomal from chromosomal DNA in the cytoplasm of mammalian cells" by 🔬 Schenkel, L., Wang, X., Le, N., Burger, M., Kroschewski, R. #bioRxiv #cellbiology http://biorxiv.org/cgi/content/short/2023.03.02.530628v1?rss=1
“Check our most recent work in collaboration with the amazing @inada_lab. The study unveils the molecular basis of eIF5A-dependent CAT tailing in eukaryotic ribosome-associated quality control. #ribosome #cryoEM #MolecularCell Here's a thread with the most exciting findings🧵...”
Reading about nonsense-mediated altered splicing. The original papers describing this phenomenon were published in #Science and #MolecularCell in 2002. Evidence that this phenomenon was probably not real was published in 2005 in #RNA.
This pattern is not exceptional. Who still remembers the claims published in #Science that #translation was nuclear ?