Today is the last day to register for the UK Membrane Traffic Meeting (organised by Chris Stefan and Jez Carlton in London).
Today is the last day to register for the UK Membrane Traffic Meeting (organised by Chris Stefan and Jez Carlton in London).
The “full collapse vs kiss-and-run” debate for synaptic vesicle fusion dates back to the 1970s. In the last 10 years ultrafast endocytosis was proposed as a reconciliation. A paper out in Science today describes “Kiss-shrink-run” and hyperfast recycling…
Their observation of vesicles that shrink upon exocytosis is cool and the technology that enabled this cryoET is very impressive. As for resolving any debate - let's see.
^ if this paper is of interest. There's a related preprint from van der Groot, Dal Peraro and D’Angelo labs:
This is cool. CryoEM showing COPI coat containing GOLPH3, together with functional data suggests the mechanism for cargo retention/transport.
The mechanistic basis of cargo selection during Golgi maturation
Taylor, Zubkov, Ciazynska et al.
Gabrielle is giving a talk today in the Warwick SLS-WMS Postdoc Association Seminar Series.
"Hacking the logic of clathrin-coated vesicle creation”
10 am in A1.51, Gibbet Hill
EMBO Workshop
From molecules to organisms: An integrative view of cell biology
16 – 21 March 2025 | Radstadt, Austria
Organised by Sharon Tooze and Marino Zerial
Deadline is 1st Dec
https://meetings.embo.org/event/25-cell-bio
And now for some new News!
This week we welcomed Anneline Moret to our lab. Anneline is a EUTOPIA co-tutelle student between our lab and Paris Cergy University. She'll be working on engineered membrane traffic of integrin in a cancer context.