After a looong journey, I can present you the results of a deep & thorough investigation of human plasma proteolysis by mass spec: SLE N-terminomics paper with a complement C3 fragment(s) is out now in EMBOJ: https://www.embopress.org/doi/full/10.1038/s44318-025-00598-8 - highlights: a nice resource on proteolytically processed N-termini in human plasma of healthy & SLE patients, with a lot of complement bonus for all interested scientists. #SLE #Science #Proteomics #TeamMassSpec #InflammatoryDisease #LupusResearch #C3 #LHF1 1/10

Der Mann hat was neues für #Lupus gefunden - oder wie @kabalak selbst sagen würde:

In conclusion, this study uncovers a new dimension of immune crosstalk: a proteolytic plasma network that generates immunoactive fragments with intrinsic self-regulatory capabilities to modulate #inflammation and tissue injury in complex disease contexts. Deciphering these immunoactivities may pave the way for innovative diagnostic and therapeutic strategies in complement-driven pathologies, potentially benefiting a wide range of inflammatory and autoimmune diseases.

#AutoimmuneDiseases #InflammatoryDisease #Science #SLE #proteomics #MassSpec #TeamMassSpec #LupusResearch

https://www.embopress.org/doi/full/10.1038/s44318-025-00598-8

Krayzie Bone Of Bone Thugs-N-Harmony Reportedly Fighting For His Life At L.A. Hospital

Prayers up for the Hip-Hop legend.

AllHipHop
A catatonic woman awakened after 20 years. Her story may change psychiatry.

New research suggests that a subset of patients with psychiatric conditions like schizophrenia may actually have autoimmune disease that attacks the brain.

Washington Post
Skin + Joints Podcast – A NATIONAL PROFESSIONALLY CURATED PODCAST ON INFLAMMATORY SKIN AND JOINT DISEASE

If you want to learn more about #HidradenitisSuppurativa please visit our website
hsheroes.ca
It's full of great information, and resources. We also have a podcast "Real Heroes Don't Wear Capes". A new episode drops at the end of every month. This month we had the pleasure of interviewing Dermatologist Dr. Chris Keeling. Who specializes in treating HS in #Edmonton Alberta.
#chronicillnes #skin #dermatology #inflammatorydisease #hsawareness #podcast #website #HSHEROES
This medication helps stop the inflammation that contributes to my HS, along with surgical intervention, and lifestyle changes. HS affects upto 4% of Canadians. My passion is to educate as many folks as possible. The more awareness will brings more treatment research for this skin disease. #chronicillness #dermatology #inflammatorydisease #CanadianSkin #hsawareness