Heather 👻Wait wait... What?!
Movies reconstructed from mouse brain activity
https://www.ucl.ac.uk/news/2026/mar/movies-reconstructed-mouse-brain-activity
PLOS BiologySLE (#lupus) is associated with genetic variants in the X-linked gene TASL. Julia Johnstone, Alex Clarke &co show that TASL is required for B cell activation, age-associated B cell formation and lupus-like disease #InMice, suggesting its potential as a therapeutic target
https://plos.io/47yDuXv
https://plos.io/47yDuXv
The adaptor protein TASL is required for age-related B cell emergence and lupus-like disease development in mice
Systemic lupus erythematosus is a chronic autoimmune disease that mostly affects women and it is associated with genetic variants in the X-linked gene encoding the adaptor protein TASL. This study shows that TASL is required for B cell activation, age-associated B cell formation and lupus-like development in a mouse model, suggesting its potential as a therapeutic target.
Why does #fat expand differently in distinct body regions? Yan Li, Carlos Ibáñez, Meng Xie &co identify Gpc3 as a gene that selectively promotes the expansion of white adipose tissue in specific body areas in mice fed a high fat diet.
#metabolism #InMice
https://plos.io/4cY5ffK
#metabolism #InMice
https://plos.io/4cY5ffK
Gpc3 selectively suppresses subcutaneous adipogenesis in diet-induced obesity
Why does fat expand differently in distinct body regions? This study identifies GPC3 as regional depot-specific obesity responsive gene that selectively promotes the expansion of inguinal, but not epididymal, white adipose tissue in mice fed a high fat diet.
Ischemic #stroke induces substantial neuronal remodeling. Huanhuan Chen, Ye Wei, Mikhail Spivakov, Oleg O Glebov &co find a loss of synapses in the ischemic core, but functional enhancement of synapses in the contralateral cortex in a mouse model of stroke.
#Neuroscience #InMice
https://plos.io/4seJxse
#Neuroscience #InMice
https://plos.io/4seJxse
Ischemic stroke triggers brain-wide synaptic remodeling within four hours
Ischemic stroke induces substantial neuronal remodeling, which is often studied in the context of mid-to-long term functional rehabilitation. This study characterizes early synaptic remodeling in a mouse model of stroke, revealing a loss of synapses in the ischemic core, but functional enhancement of synapses in the contralateral cortex.
quangobaudMice playing Doom
(sadly, no gameplay images 🙁)
#GabrielTorch #BearBaitOfficial #Science #RunningDoomOn #InMice
Rats Trained To Play Doom In VR Can Now Shoot Opponents
earliest evidence of chavs caught doing arson! 😱
Nature
https:// www.nature .com › articles › s41586-025-09855-6
Earliest evidence of making fire - Nature
Today
Here we present evidence of fire-making on a 400,000-year-old buried landsurface at Barnham (UK), where heated sediments and fire-cracked flint
(also this should say #InMice .. whoops ... I meam #OldestEvidenceButNotOldestInTheWorldJustOldestInTheUK )
Damian YerrickDon't give your pet mouse 🐁️ a tattoo. A study by Capucetti et al. in PNAS found the ink lingers in lymph nodes for months and kills immune cells. Effect on vaccines varied; Comirnaty (for COVID) injected into a tattoo was weaker while the flu jab was stronger.
https://www.consumeraffairs.com/news/tattoo-ink-races-into-lymph-nodes-kills-immune-cells-and-alters-vaccine-responses-study-finds-120225.html
Avi Rappoport (avirr)
WearyBonnieYou know that thing where people add #InMice to posts about scientific discoveries where the research has so far only been done on mice?
We need #InTheEast for stories about 'Australian' weather conditions 😐
We need #InTheEast for stories about 'Australian' weather conditions 😐
Alex von Kitchen