@eLife
New work on the #chinmo gene that controls fly larval development, by Sílvia Chafino et al. 2023 https://elifesciences.org/articles/84648
… building on prior work by Truman & Riddiford 2022 https://www.pnas.org/doi/abs/10.1073/pnas.2201071119 on “Chinmo is the larval member of the molecular trinity that directs Drosophila metamorphosis”
#Drosophila #DevBiol #metamorphosis
Antagonistic role of the BTB-zinc finger transcription factors Chinmo and Broad-Complex in the juvenile/pupal transition and in growth control
Stage identity and developmental progression in insects is controlled by sequential expression of temporal-specific transcription factors.
“Importantly, we also provide evidence that, in contrast to the well-known role of chinmo as a pro-oncogene, Br-C and E93 act as tumour suppressors.”
#dna #isogg #chinmo #epigenetics #geneadons #cancer #tumorsupressors https://elifesciences.org/articles/84648Antagonistic role of the BTB-zinc finger transcription factors Chinmo and Broad-Complex in the juvenile/pupal transition and in growth control
Stage identity and developmental progression in insects is controlled by sequential expression of temporal-specific transcription factors.
Scientists Discover Chinmo – “The Youth Gene”
Researchers discover Chimno, the gene responsible for the juvenile stage in insects. This gene is present in mammals and could play a key role in cancerous processes.
https://scitechdaily.com/scientists-discover-chinmo-the-youth-gene/ #chinmo #youth #gene #insects #mammals
Scientists Discover Chinmo – “The Youth Gene”
Researchers discover Chimno, the gene responsible for the juvenile stage in insects. This gene is present in mammals and could play a key role in cancerous processes. The study, which was published in the journal eLife and led by the Institute for Evolutionary Biology (IBE, CSIC-UPF) and the IRB
Researchers discover Chinmo, 'the youth gene'
A new study published on eLife and led by the Institute for Evolutionary Biology (IBE, CSIC-UPF) and the IRB Barcelona, has revealed that the Chinmo gene is responsible for establishing the juvenile stage in insects. It also confirms that the Br-C and E93 genes play a regulatory role in insect maturity. These genes, which are also present in humans, act as a promoter and as a suppressor, respectively, of cancerous processes.
Albert Cardona
ISOGG
Matt Willemsen
CellBioNews