🔬📄 'In vivo Inhibition of Helicobacter pylori through Probiotics and Gastrointestinal Commensals: A Critical Review' - a Karger: #Gastroenterology article on #ScienceOpen -

🔗 https://www.scienceopen.com/document?vid=38fda4e5-d0c6-4b1f-8f89-3cc8cf384079

#HelicobacterPylori #Probiotics #Lactobacillus #Bifidobacterium #Microbiota

In vivo Inhibition of <i>Helicobacter pylori</i> through Probiotics and Gastrointestinal Commensals: A Critical Review

<p xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" dir="auto" id="d7337970e228"> <b> <i>Background:</i> </b> <i>Helicobacter pylori</i> eradication is increasingly challenged, due to high antibiotic resistance rates in <i>H. pylori</i> and treatment failure. Consequently, new treatment regimens are needed. Probiotic and gastrointestinal bacteria exert anti- <i>H. pylori</i> activity in vivo, thus being potential add-on candidates for future eradication strategies. <b> <i>Summary:</i> </b> In this review, we summarised the currently available literature for in vivo inhibition of <i>H. pylori</i>. Included studies address anti- <i>H. pylori</i> effects in mouse and rat models caused by potentially beneficial bacteria. Research on literature was further extended to clinical eradication studies in humans. Several bacterial strains, mainly belonging to the <i>Lactobacillus</i> genus, inhibited <i>H. pylori</i> in vivo. In animal studies, probiotic bacteria and commensals reduced <i>H. pylori</i> colonisation and the inflammatory response. Certain probiotic species reduce <i>H. pylori</i> colonisation in humans. <b> <i>Key Messages:</i> </b> Probiotic and gastrointestinal commensals are beneficial in <i>H. pylori</i> eradication therapy. Their current role is the reduction of adverse events and <i>H. pylori</i> load. </p>

ScienceOpen

https://medicalxpress.com/news/2025-07-beneficial-bacteria-infant-guts-linked.html

Missing beneficial bacteria in infant guts linked to rising asthma and allergy cases

researchers highlight that while the term #dysbiosis or imbalance in the #microbiome is still up for debate, the strong correlation between microbiome composition and #infanthealth suggests that the absence of these key #Bifidobacterium strains represents a true dysbiosis in early life.

Missing beneficial bacteria in infant guts linked to rising asthma and allergy cases

Nearly one in four infants lacks enough healthy gut bacteria essential for training their immune systems, putting them at greater risk of developing non-communicable diseases (NCDs) such as allergies, asthma, and eczema by age 2.

Medical Xpress

Examination of 412 U.S. infants (1-3 months old) found low levels of the Bifidobacterium in the intestines of most, with 25% of them lacking the bacterium entirely. Low levels of Bifidobacterium in infants were associated with greater incidences of allergies, eczema, and dermatitis in 210 individuals who were assessed at age 2.

Summary: https://www.sciencenews.org/article/babies-gut-bacteria-allergies-asthma

Original paper: https://www.nature.com/articles/s42003-025-08274-7

#Science #Microbiome #Allergies #Eczema #Bifidobacterium

Many U.S. babies may lack gut bacteria that train their immune systems

Too little Bifidobacterium, used to digest breast milk, in babies' gut microbiomes can increase their risk of developing allergies and asthma.

Science News

Bifidobacterium vs. Lactobacillus probiotics: what’s the difference?
https://www.mygenefood.com/blog/bifidobacterium-vs-lactobacillus-strains/

article includes a nice comparison chart

#GutMicrobiome #probiotics #Bifidobacterium #Lactobacillus

Understanding probiotics: Bifidobacterium vs Lactobacillus | Gene Food

The microbiome is composed of a huge number of microflora that work together to regulate health, but two of the most focused on in the supplement industry are Bifidobacterium and Lactobacillus. Can these strains be put together? What are the differences between Bifidobacterium and Lactobacillus? Is one better for us?

Gene Food
From 03 Oct: Popular gut probiotic completely craps out in randomized controlled trial - Any striking marketing claims in companies’ ads about the gut benefits of a popular probiotic may be... https://arstechnica.com/health/2024/10/popular-gut-probiotic-completely-craps-out-in-randomized-controlled-trial/ #activia #b.-lactis #bifidobacterium-animalis-subsp.-lactis #constipation #digestive-disorder #digestive-system #functional-constipation #health #probiotic #science #yogurt
Popular gut probiotic completely craps out in randomized controlled trial

If you’re familiar with the history of Activia, you may not be surprised.

Ars Technica

Gut microbes can affect COVID vaccine response.

by Karolinska Institutet

ORIGINAL PAPER
Shilpa Ray et al, Impact of the gut microbiome on immunological responses to COVID-19 vaccination in healthy controls and people living with HIV, npj Biofilms and Microbiomes(2023). DOI: 10.1038/s41522-023-00461-w

https://www.nature.com/articles/s41522-023-00461-w

#Bifidobacterium #Faecalibacterium #Cloacibacillus #IgG #gutMicrobiome

Impact of the gut microbiome on immunological responses to COVID-19 vaccination in healthy controls and people living with HIV - npj Biofilms and Microbiomes

Although mRNA SARS-CoV-2 vaccines are generally safe and effective, in certain immunocompromised individuals they can elicit poor immunogenic responses. Among these individuals, people living with HIV (PLWH) have poor immunogenicity to several oral and parenteral vaccines. As the gut microbiome is known to affect vaccine immunogenicity, we investigated whether baseline gut microbiota predicts immune responses to the BNT162b2 mRNA SARS-CoV-2 vaccine in healthy controls and PLWH after two doses of BNT162b2. Individuals with high spike IgG titers and high spike-specific CD4+ T-cell responses against SARS-CoV-2 showed low α-diversity in the gut. Here, we investigated and presented initial evidence that the gut microbial composition influences the response to BNT162b2 in PLWH. From our predictive models, Bifidobacterium and Faecalibacterium appeared to be microbial markers of individuals with higher spike IgG titers, while Cloacibacillus was associated with low spike IgG titers. We therefore propose that microbiome modulation could optimize immunogenicity of SARS-CoV-2 mRNA vaccines.

Nature

For all their bullshit the right does pick up on some weirdo cultural trend that I think they are correct about every now and then.

I think the idea of consuming human breast milk later in life is going to be the cure to a lot of the #microbiome issues that our society is having now. It obviously needs to be tested for pathogens because those can be transferred but what is considered a healthy microbiome largely consists of that which is transplanted during birth and via breast milk.

We know that specific strains which are plentiful in youth such as #Bifidobacterium decline to make up only about 10% of the microbiome in late 20s and nearly die off completely by 30s. We also know that specific #Lactobacillus strains such as lactobacillus reuteri have declined on the whole since the 90s in US populations both of which are found in breast milk.

We are likely going to find that colonization of the gut requires an entire ecostystem and this is likely why #probiotics on the whole are not useful for altering the micrbiome long term. Breast milk which includes a diverse ecosystem of microbes as well as Oligosaccharides and Lactoferrin being required by the process. Thus far the long term efficacy of Fecal matter transplants ie #FMT being questionable at best is a possible alternative to this.

#Health #PersonalHealth #Dsybosis

We found that protocols including the probiotic #Bifidobacterium longum subsp. infantis lead to an earlier maturation of the gastrointestinal tract, better human milk oligosaccharides (#HMOs) digestion, and a lower presence of antibiotic resistance genes.
The #bacteria, #Bifidobacterium breve, is widely used as a #probiotic so this study could point to ways of combating #pregnancy complications and ensuring a healthy start in life across the population.
#Microbiology #Medical #Biology #sflorg
https://www.sflorg.com/2022/06/mcb06212201.html
Maternal microbiome promotes healthy development of the baby

Researchers studying mice have found the first evidence of how a mother’s gut microbes can help in the development of the placenta