Mastodawn

SPAAM-community Jul 22, 2024

#MetagenomicsMonday 🧬 Ancient viral DNA reveals historical #pathogens aiding understanding of virus evolution.
#paleogenetics #ancientpathogens #metagenomics #viralDNA #virusevolution
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10063219/

An Adagio for Viruses, Played Out on Ancient DNA

Studies of ancient DNA have transformed our understanding of human evolution. Paleogenomics can also reveal historic and prehistoric agents of disease, including endemic, epidemic, and pandemic pathogens. Viruses—and in particular those with single- ...

PubMed Central (PMC)

King_Moosa May 10, 2024

Dive into the intricate dance of COVID-19 variants! Unravel the mystery behind their flirtatious behavior with our detailed analysis. Stay ahead of the curve with the latest insights on pandemic dynamics. 👉 https://t.ly/4oBnK
#COVID19 #Variants #PublicHealth #VirusEvolution

Unraveling the FLiRT of COVID-19 Variants: Understanding Their Impact on Infections

Unlock insights into FLiRT COVID-19 variants: their impact, characteristics, and implications. Stay informed for safer choices

NIOO-KNAW Mar 6, 2024

New NIOO publication: Robust Approaches to the Quantitative Analysis of Genome Formula Variation in Multipartite and Segmented #Viruses.
#virusecology #plantvirus #virusevolution
https://doi.org/10.3390/v16020270

Robust Approaches to the Quantitative Analysis of Genome Formula Variation in Multipartite and Segmented Viruses

When viruses have segmented genomes, the set of frequencies describing the abundance of segments is called the genome formula. The genome formula is often unbalanced and highly variable for both segmented and multipartite viruses. A growing number of studies are quantifying the genome formula to measure its effects on infection and to consider its ecological and evolutionary implications. Different approaches have been reported for analyzing genome formula data, including qualitative description, applying standard statistical tests such as ANOVA, and customized analyses. However, these approaches have different shortcomings, and test assumptions are often unmet, potentially leading to erroneous conclusions. Here, we address these challenges, leading to a threefold contribution. First, we propose a simple metric for analyzing genome formula variation: the genome formula distance. We describe the properties of this metric and provide a framework for understanding metric values. Second, we explain how this metric can be applied for different purposes, including testing for genome-formula differences and comparing observations to a reference genome formula value. Third, we re-analyze published data to illustrate the applications and weigh the evidence for previous conclusions. Our re-analysis of published datasets confirms many previous results but also provides evidence that the genome formula can be carried over from the inoculum to the virus population in a host. The simple procedures we propose contribute to the robust and accessible analysis of genome-formula data.

MDPI

Denis - The COVID info guy -Feb 23, 2024

"Persistent SARS-CoV-2 infections may act as viral reservoirs that could seed future outbreaks, give rise to highly divergent lineages, and contribute to cases with post-acute COVID-19 sequelae (long COVID)"

Source: https://www.news-medical.net/news/20240222/Persistent-COVID-19-could-drive-virus-evolution-new-study-suggests.aspx

Study: https://www.nature.com/articles/s41586-024-07029-4

#COVID19 #VirusEvolution @auscovid19

Persistent COVID-19 could drive virus evolution, new study suggests

Study reveals the prevalence of persistent SARS-CoV-2 infection in the UK, showing its potential role in viral evolution and the emergence of new variants, with implications for long-COVID and public health strategies.

News-Medical

Victor M. Corman Mar 31, 2023

A long project is now finally completed and published. "Non-structural genes of novel lemur adenoviruses reveal codivergence of virus and host." Congrats to Tali on this publication.
https://doi.org/10.1093/ve/vead024
#VirusEvolution #CharitéVirology #Charite
#Lemur

Enrico Bucci Mar 3, 2023

L'INFLUENZA DEL MARE

Certi virus acquatici, a quanto pare, sono parte di una sola grande famiglia con quelli terrestri dell'influenza.
La cosa non è priva di conseguenze.

#virusevolution

https://www.ilfoglio.it/scienza/2023/03/03/news/da-dove-vengono-i-virus-come-quello-dell-influenza--5014743/

Da dove vengono i virus come quello dell'influenza?

Non solo Venere è emersa dalla spuma marina, ma anche qualche fastidioso o pericoloso coinquilino di questo pianeta

Ginny Mooy Feb 1, 2023

𝗗𝗲𝗲𝗿 𝗖𝗼𝘂𝗹𝗱 𝗕𝗲 𝗮 𝗥𝗲𝘀𝗲𝗿𝘃𝗼𝗶𝗿 𝗼𝗳 𝗢𝗹𝗱 𝗖𝗼𝗿𝗼𝗻𝗮𝘃𝗶𝗿𝘂𝘀 𝗩𝗮𝗿𝗶𝗮𝗻𝘁𝘀, 𝗦𝘁𝘂𝗱𝘆 𝗦𝘂𝗴𝗴𝗲𝘀𝘁𝘀

"The Alpha and Gamma variants of the coronavirus continued to circulate and evolve in white-tailed deer, even after they stopped spreading widely among people, a new study suggests.

Whether the variants are still circulating in deer remains unknown."

#VirusEvolution #COVID #Pandemic

https://www.nytimes.com/2023/01/31/health/coronavirus-variants-deer.html

Deer Could Be a Reservoir of Old Coronavirus Variants, Study Suggests

Even after Delta became the dominant variant in humans, Alpha and Gamma continued to circulate in white-tailed deer, according to new research.

Ginny Mooy Jan 31, 2023

'We're three years into the COVID-19 pandemic. What might the virus do next?'

#COVID #Pandemic #VirusEvolution

https://www.abc.net.au/news/health/2023-01-31/three-years-covid-19-pandemic-virus-evolution-subvariants/101900226?utm_campaign=abc_news_web&utm_content=twitter&utm_medium=content_shared&utm_source=abc_news_web

We're three years into the COVID-19 pandemic. What might the virus do next?

It’s been three long years since the World Health Organization declared COVID-19 a global health emergency. So what can we expect the virus to do next?

ABC News

Matt Hodgkinson Dec 2, 2022

Rather than having evolved in an immunocompromised person in South Africa as suspected, Omicron seems to have evolved in steps while circulating in West Africa during summer 2021 before exploding across the south that autumn.
https://www.science.org/doi/10.1126/science.add8737

#ViralEvolution #Omicron #SarsCoV2 #Virology #WestAfrica #SouthAfrica #Immunocompromised #COVID19 #OriginOfCovid #ScienceMagazine #Phylogenetics #VirusEvolution #BA1 #VariantsOfSARSCoV2 #ViralGenetics #Epidemiology #InfectiousDiseaseEpidemiology