Jody Corcoran: Covid is back and so too is the extreme fatigue

I write this weak at the knees, after a two-hour sleep on the couch. If I get to the end before fatigue sets in, I will be doing well. Yes, folks, Covid is back, and I have it – again. Only this time it feels different.

Independent.ie

@Covidcanada @kudra
idk about sterilizing especially w/mutated #variantsofsarscov2
Took me nearly 2 yrs to figure out my SO was an #asymptomatic spreader who would carry for 4 days & never get full infection
Recently that changed somewhat as he actually appears wee sick for those 4-5 days..

Imho do think #Novavax does what #mRNA promised but doesn’t deliver

The kidney soreness for months after Pfizer is primary reason I won’t do it; felt similar to acute Covid but again anecdotal🤷🏻‍♀️

https://www.usatoday.com/story/news/health/2023/01/06/covid-update-xbb-variant-symptoms-reinfection/10995204002/
They had me until the last paragraph. Actually headline wasn’t great either. Is this how they teach writing now?

How about they tell the public just exactly how #XBB15 came about & what implications that has for future #variantsofsarscov2

People are indoctrinated with so many untruths, it must be safe to partially tell some truths now

Altogether a minimizing article & most will not understand the gravity of this situation🙄
#CovidIsNotOver #wearADamnMask #gaslighting

People who haven't had COVID will likely catch XBB.1.5 – and many will get reinfected, experts say

New COVID variant XBB.1.5 is very contagious, meaning everyone is at risk for infection even if you've already had COVID. Here's what that means.

USA TODAY

▶️Orf3a:A54V est le retour d'une mutation de la souche Wuhan arrivée très tôt en 2020. Orf3a, propre aux SARS, joue plusieurs rôles, dont un pathogène inflammatoire (cytokine storm).

Voir réapparaître des mutations de début 2020 dessus n'est jamais rassurant.

#Covid19 #Variant #VariantSoup #variantsofsarscov2

▶️Les mutations en 852-859 (fusion peptide proximal région) S2 de Spike sont convergentes depuis peu, mais apparaissent aussi dans des mutations d'immunodeprimés chroniques. Leur avantage peut-être sur la fusion cellulaire.

Ce variant progresse rapidement.

#Covid19 #Variant #VariantSoup #variantsofsarscov2

THREAD nouveau variant

BQ.1.25 devient brutalement intéressant (Amerique, Australie)

BQ.1.25▶️BQ.1 + S:R346T
BQ.1.25.1▶️BQ.1.25 + S:L858I + ORF3a:A54V

▶️S:R346T l'amène au niveau de BQ.1.1 en échappement immunitaire.

#Covid19 #Variant #VariantSoup #variantsofsarscov2

Nouveau variant :

Sur la branche BA.5.1.25* :

DJ.1.3▶️DJ.1 + S:N460K + ORF1ab:T6098A

4 mutations d'échappement immunitaire ++
2 mutations d'échappement immunitaire +

▶️ORF1ab:T6098A : Mutation inédite dans l'ExoN de NSP14, système de correction d'erreurs à la réplication qui gène la recherche d'antiviraux

#Covid19 #Variant #VariantSoup #variantsofsarscov2

https://amp.theguardian.com/world/2022/dec/19/china-covid-waves-winter-cities-quiet
interesting🇨🇳chief epidemiologist warning of 3 winter waves based on holidays but probs also in anticipation of different #variantsofsarscov2 burning through

How many waves for spring & summer?

I mean, they’re totally lying about #Covid deaths #coverUp but at least they are warning people unlike some countries… #ABC #MERS #Ebola #RSV 🙄🙄

China’s cities fall quiet amid warning of three Covid waves over winter

Chief epidemiologist says China is in the first of an expected three waves of Covid cases, despite official figures showing low numbers

The Guardian
And with it, 1.2 billion possible #variants #VariantSoup #variantsofsarscov2

Rather than having evolved in an immunocompromised person in South Africa as suspected, Omicron seems to have evolved in steps while circulating in West Africa during summer 2021 before exploding across the south that autumn.
https://www.science.org/doi/10.1126/science.add8737

#ViralEvolution #Omicron #SarsCoV2 #Virology #WestAfrica #SouthAfrica #Immunocompromised #COVID19 #OriginOfCovid #ScienceMagazine #Phylogenetics #VirusEvolution #BA1 #VariantsOfSARSCoV2 #ViralGenetics #Epidemiology #InfectiousDiseaseEpidemiology