Giuseppe Michieli#Tissue #tropism and functional #adaptation of the #SARS-CoV-2 #spike protein in a #fatal case of #COVID19, https://etidiohnew.blogspot.com/2025/10/tissue-tropism-and-functional.html
#H3N2 #influenza virus #tropism shifts to glycan #receptors on tracheal ciliated cells, https://etidiohnew.blogspot.com/2025/09/h3n2-influenza-virus-tropism-shifts-to.html
Viral #tropism is a cornerstone in the spread and #spillover of avian #influenza viruses, https://etidiohnew.blogspot.com/2025/07/viral-tropism-is-cornerstone-in-spread.html
#Pathology of #Influenza A (#H5N1) #infection in #pinnipeds reveals novel tissue #tropism and vertical #transmission., https://etidiohnew.blogspot.com/2025/02/pathology-of-influenza-h5n1-infection.html
Planetary EcologistHeliotropism (Botany 🌱)
Heliotropism, a form of tropism, is the diurnal or seasonal motion of plant parts in response to the direction of the Sun. The habit of some plants to move in the direction of the Sun, a form of tropism, was already known by the Ancient Greeks. They named one of those plants after that property Heliotropium, meaning "sun turn". The Greeks assumed it to be a passive effect, pr...
#Receptor #binding, #structure, and #tissue #tropism of #cattle-infecting #H5N1 avian #influenza virus #hemagglutinin, https://etidiohnew.blogspot.com/2025/01/receptor-binding-structure-and-tissue.html
Enhanced #encephalitic #tropism of #bovine #H5N1 compared to the #Vietnam #H5N1 isolate in #mice
Source: BioRxIV, AbstractIn recent years, the landscape of highly pathogenic avian influenza (HPAI) virus infections has shifted, as evidenced by an increase in infections among mammals. This includes the recent circulation of H5N1 in dairy cattle herds in the USA and a rise in associated human cases. In this study, we investigated differences in tissue tropism…
Enhanced #encephalitic #tropism of #bovine #H5N1 compared to the #Vietnam #H5N1 isolate in #mice
Source: BioRxIV, AbstractIn recent years, the landscape of highly pathogenic avian influenza (HPAI) virus infections has shifted, as evidenced by an increase in infections among mammals. This inclu…
The #host #tropism of current #zoonotic #H7N9 viruses depends mainly on an acid-labile #hemagglutinin with a single amino acid #mutation in the #stalk region
Source: PLoS Pathogens, AbstractThe incidence of human infection by zoonotic avian influenza viruses, especially H5N1 and H7N9 viruses, has increased. Current zoonotic H7N9 avian influenza viruses (identified since 2013) emerged during reassortment of viruses belonging to different subtypes. Despite analyses of…
The #host #tropism of current #zoonotic #H7N9 viruses depends mainly on an acid-labile #hemagglutinin with a single amino acid #mutation in the #stalk region
Source: PLoS Pathogens, AbstractThe incidence of human infection by zoonotic avian influenza viruses, especially H5N1 and H7N9 viruses, has increased. Current zoonotic H7N9 avian influenza viruses …
Enhanced Diversifying #Selection on #Polymerase Genes in #H5N1 Clade 2.3.4.4b: A Key Driver of Altered #Species #Tropism and #Host Range Expansion, BioRxIV: https://www.biorxiv.org/content/10.1101/2024.08.19.606826v1?rss=1
the polymerase genes #PB2, #PB1, and #PA exhibit significantly greater selection pressures in clade 2.3.4.4b than in all the earlier H5N1 virus clades. Polymerases play critical roles in influenza virus adaptation, including viral fitness, interspecies transmission, and virulence.
In #turkeys, unlike #chickens, non-structural #NS1 #protein does not play a significant role in #replication and tissue #tropism of the #H7N1 avian #influenza virus, Virulence: https://www.tandfonline.com/doi/full/10.1080/21505594.2024.2379371
These results suggest that NS1 does not play a role in the virulence or replication of HPAIV H7N1 in turkeys and further indicate that #genetic determinants of HPAIV differ in these two closely related galliform species.