Mastodawn

JIPB Aug 5, 2024

Is your Monday being *extra* Monday-ish?
Would some free #PlantScience help?
Then we've got good news for you!

Find out how α1-COP modulates #plasmodesmata function in this new #JIPB paper by Iswanto et al.
🔓⬇️
https://doi.org/10.1111/jipb.13711
@wileyplantsci
#Arabidopsis #sphingolipid #desmotubule #botany #OpenAccess

JIPB Aug 22, 2023

Up for a road trip?🚗
Sphingolipids act as signaling molecules in many cellular processes. Join us on this adventure to learn more about the #sphingolipid #biosynthetic pathway!🛣️
https://doi.org/10.1111/jipb.13461
@wileyplantsci
#PlantScience #JIPB #Arabidopsis #signaling #PlasmaMembrane

JIPB Jul 10, 2023

Sphingolipids are important for #membrane lipid bilayer structure and act as signaling molecules in many #cellular processes. But what do we actually know about the #sphingolipid #biosynthetic pathway in #Arabidopsis?🔓⬇️
https://doi.org/10.1111/jipb.13461
@wileyplantsci
#PlantSci #PlantScience

JIPB Mar 3, 2023

Li et al. report that #phosphorylation of the serine palmitoyltransferase LCB1 subunit stimulates its activity and modulates #sphingolipid #biosynthesis in #Arabidopsis.
https://doi.org/10.1111/jipb.13461
@wileyplantsci
#PlantScience #JIPB #signaling #PlasmaMembrane

Biology Open Jan 24, 2023

Siti Nur Sarah Morris and colleagues carry out a genome-wide #CRISPR screen and reveal a role for TMEM30A-regulated #membrane assembly in determining #cancer cell sensitivity to ceramide-induced cell death:

https://journals.biologists.com/bio/article/11/12/bio059695/286108/A-genome-wide-CRISPR-screen-implicates-plasma

#Screen #Lipids #Sphingolipid #Lipotoxicity #Science #BiologyOpen #Biology #Science #AcademicMastodon

genome-wide CRISPR screen implicates plasma membrane asymmetry in exogenous C6-ceramide toxicity

Summary: A genome-wide CRISPR screen reveals a role for TMEM30A-regulated membrane asymmetry in governing cancer cell sensitivity to ceramide-induced cell death.

The Company of Biologists