#GoodNews: Ein einst abgelehntes HIV-Medikament könnte die Hirnplastizität revolutionieren! #Maraviroc – ursprünglich gegen HIV – wird nun als „Neuroreha-Pille“ getestet. Es könnte nach Schlaganfall oder Trauma das „Umlern-Fenster“ des Gehirns verlängern & Patienten neue Chancen auf Genesung geben – selbst wenn klassische Reha schon beendet ist. 🧠✨

via: Fix The News

https://www.nytimes.com/2025/09/04/science/neuroscience-brain-injury-pill.html?unlocked_article_code=1.lE8.a6yp.KKMz_fI3UyeT&smid=url-share

Could a Pill Fix the Brain?

Neurologists are exploring medications that would help the brain recover after a stroke or traumatic injury.

The New York Times
Mount Sinai Receives $2.6 Million Grant From PolyBio Research Foundation for Long COVID Clinical Trials

Funding will also support researching other complex illnesses and medical education

Mount Sinai Health System
Double Duty: HIV Drug Maraviroc Takes On Dementia and Huntington’s Disease
Researchers at the University of Cambridge have found a way to enhance the brain’s self-cleaning process (autophagy) in mice with Huntington’s disease and dementia. They discovered that an existing HIV drug, maraviroc, can inhibit a switch (CCR5) that impairs autophagy, leading to a reduction in harmful protein build-up and potentially slowing down memory loss.
https://scitechdaily.com/double-duty-hiv-drug-maraviroc-takes-on-dementia-and-huntingtons-disease/ #HIVDrug #Maraviroc #Dementia #HuntingtonsDisease #autophagy #neurodegenerative
Double Duty: HIV Drug Maraviroc Takes On Dementia and Huntington’s Disease

HIV drug helps protect against build-up of dementia-related proteins in mouse brains. Cambridge scientists have shown how the brain’s ability to clear out toxic proteins is impaired in Huntington’s disease and other forms of dementia – and how, in a study in mice, a repurposed HIV drug was able t

SciTechDaily
#ScifiVsReality Research shows an HIV drug, #Maraviroc, appears to help the brain eliminate toxic proteins that lead to Huntington's disease and a type of dementia, raising the possibility that it could be repurposed as a therapy for such diseases. https://bit.ly/3ACl3R6
HIV drug shown to help protect against build-up of dementia-related proteins in mouse brains

Cambridge scientists have shown how the brain's ability to clear out toxic proteins is impaired in Huntington's disease and other forms of dementia—and how, in a study in mice, a repurposed HIV drug was able to restore this function, helping prevent this dangerous build-up and slowing progression of the disease.

Medical Xpress