Local and introduced #lineages drive #MERS-CoV #recombination in Egyptian #camels

Genetic #reassortment and diversification of #host specificity have driven evolutionary trajectories of #lineages of #panzootic #H5N1 #influenza

Co-Circulation of 2 #Oropouche Virus #Lineages during #Outbreak, #Amazon Region of #Peru, 2023–2024

Co-Circulation of 2 #Oropouche Virus #Lineages, #Amazon Basin, #Colombia, 2024

Source: Emerging Infectious Diseases Journal, AbstractIn early 2024, explosive outbreaks of Oropouche virus (OROV) linked to a novel lineage were documented in the Amazon Region of Brazil. We repor…

A new lineage nomenclature to aid genomic surveillance of dengue virus

Dengue virus (DENV) is causing increasingly larger and more widespread epidemics, which makes it critical to track the virus using genomic surveillance, but there is currently no suitable system to classify circulating variants. This Consensus View proposes a new DENV nomenclature system and free online tools to identify and track lineages of potential epidemiological and/or clinical importance.

Virulence and transmission vary between Usutu virus lineages in Culex pipiens

Author summary Usutu virus is a zoonotic arbovirus that emerged in the last decade in Europe, impacting wild bird and human populations. Several co-circulating USUV lineages differ in their virulence to vertebrate hosts but their relative transmission and effects on their mosquito vectors is still not known. We compared the vector competence and survival of Culex pipiens mosquitoes experimentally infected with two distinct USUV lineages. We showed that their relative transmission efficiencies are similar but EU3 was more virulent to mosquitoes than EU2. In addition to published results, we revealed lineage-specific differences in vectorial capacity and virulence to both the vector and the vertebrate host suggesting that propagation of both viral lineages might be balanced. Our study provides new insights into the transmission of an emerging arbovirus and highlights the need to investigate the interactions between vectors, vertebrate hosts, and the diversity of arbovirus lineages to fully understand transmission dynamics.

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@RajlabN: Tracking #SARSCoV2 #Lineages - Globally |05/18/24 Top lineages -#30DayTrends (#G30) KP.2 (12.7%) KP.3 (11.6%)👀 JN.1.7 (6.9%) JN.1 (6.8%) JN.1.16 (5%) JN.1.4 (4.9%) JN.1.16.1 (4.6%) KP.1.1 (3.6%) KS.1 (2.8%)...…

H6N2 reassortant avian influenza virus isolate in wild birds in Jiangxi Province, China - Virus Genes

H6 avian influenza virus is widely prevalent in wild birds and poultry and has caused human infection in 2013 in Taiwan, China. During our active influenza surveillance program in wild waterfowl at Poyang Lake, Jiangxi Province, an H6N2 AIV was isolated and named A/bean goose/JiangXi/452-4/2013(H6N2). The isolate was characterized as a typical low pathogenic avian influenza virus (LPAIV) due to the presence of the amino acid sequence PQIETR↓GLFGAI at the cleavage site of the hemagglutinin (HA) protein. The genetic evolution analysis revealed that the NA gene of the isolate originated from North America and exhibited the highest nucleotide identity (99.29%) with a virus recovered from wild bird samples in North America, specifically A/bufflehead/California/4935/2012(H11N2). Additionally, while the HA and PB1 genes belonged to the Eurasian lineage, they displayed frequent genetic interactions with the North American lineage. The remaining genes showed close genetic relationships with Eurasian viruses. The H6N2 isolate possessed a complex genome, indicating it is a multi-gene recombinant virus with genetic material from both Eurasian and North American lineages.