Charo del Genio6d ago

New paper, with Zerong Guo, Zonghua Liu, Shuguang Guan, Stefano Boccaletti and Jie Zhou.

Everyone knows about chimera states. We show a new mechanism for the emergence of chimeras that is specific of higher-order interactions. Interestingly, this mechanism is somewhat analogous to what happens in some proteins with intrinsic disorder (which we showed a couple of years ago), so we called it intrinsic frustration.

#mathematics #physics #science #HigherOrderNetworks #synchronization #DynamicalSystems #ChimeraStates #chimeras #frustration #IntrinsicDisorder

michaelJun 14, 2024

13-JUN-2024
Developing a system to study proteins without fixed structures
Researchers propose a novel pipeline that makes the analysis of intrinsically disordered proteins much faster and more convenient

I do love #IntrinsicallyDisorderedProteins but pinning them down to do a crystal structure is kind of against the spirit? NMR structures giving dynamic representations have served the field well

https://www.eurekalert.org/news-releases/1048185 #science #proteins #structuralBiology #IntrinsicDisorder

Developing a system to study proteins without fixed structures

Intrinsically disordered proteins (IDPs) can dynamically change their conformations depending on their external environment and can, therefore, bind to different compounds. However, they are difficult to analyze. Now, Tokyo Tech researchers have addressed this issue with a novel pipeline that enables a rapid crystal structure analysis of IDPs via a cell-free protein crystallization technique.

EurekAlert!