"Hoy quiero compartir contigo una noticia que me llena de esperanza. Investigadores están trabajando en un nuevo protocolo que combina la estimulación magnética transcranial y la estimulación eléctrica para mejorar la función de las extremidades inferiores en personas con lesiones médullares incompletas. ¡Es un paso hacia la recuperación y la independencia! ¿Qué te parece? ¿Qué estrategias usas para superar desafíos diarios? #Neurociencia #Resiliencia #Grit"
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0345100
Background Spinal cord injury (SCI) is a neurological condition that affects thousands of individuals globally each year. Among its many consequences, lower extremity impairments, including reduced walking function, balance deficits, and muscle weakness, significantly impact mobility and quality of life. Various rehabilitation approaches aim to restore function, including neuromodulation strategies, such as functional electrical stimulation (FES) cycling and repetitive transcranial magnetic stimulation (rTMS). While both interventions have shown effectiveness in improving lower extremity function following SCI, they have yet to be performed together to determine the combined effectiveness. This pilot trial will evaluate the feasibility and safety of combining rTMS and FES cycling in people with motor incomplete SCI (iSCI) and provide information to determine a sample size for a full randomized controlled trial. Secondary outcomes will explore the effectiveness of the combined intervention on lower extremity function. Methods This is a pilot randomized controlled trial with assessor and participant blinding. Fourteen participants will be randomized to receive either active or sham rTMS prior to FES cycling for a total of 12 sessions over six weeks. Functional outcomes, including gait parameters, muscle strength, and balance tests, will be assessed at baseline, midpoint, post-intervention, and two weeks following treatment cessation and will be assessed both within and between groups to explore trends in efficacy. Feasibility and safety data will be analyzed descriptively. Implications This study aims to establish a protocol and sample size for running a full randomized controlled trial on the effectiveness of combining rTMS and FES cycling for lower extremity rehabilitation in iSCI. The protocol is registered with ClinicalTrials.gov (ID: NCT05975606).
"¡Excelente noticia para todos nosotros! Los científicos han descubierto cómo funciona el medicamento Lecanemab para la Alzheimer. Resulta que activa las células inmunitarias del cerebro, pero solo a través de una parte específica del anticuerpo llamada Fc. Esto nos ofrece esperanza para nuevos tratamientos. ¿Qué te parece si empezamos a hablar de cómo podemos apoyar nuestro cerebro para mantenerlo fuerte y saludable? #Neurociencia #Resiliencia #Grit"
https://www.sciencedaily.com/releases/2026/03/260317064457.htm
A key Alzheimer’s drug has finally revealed its secret. Researchers discovered that lecanemab works by activating the brain’s immune cells—but only through a specific part of the antibody called the Fc fragment. This piece acts like a trigger, prompting microglia to clear harmful amyloid plaques. The finding could reshape how future Alzheimer’s therapies are designed.
"¡Descubre la magia del ritmo! Investigadores han encontrado un vínculo biológico entre la música y la conexión emocional. Escuchar música que te hace sentir conectado con alguien puede aumentar las hormonas del afecto y fortalecer la química entre ustedes. ¡Así que no te sorprendas si te sientes más conectado con tu mejor amigo cuando escuchan una banda común!" #Neurociencia #Resiliencia #Grit
https://neurosciencenews.com/biological-link-between-music-and-bonding-identified/
"The distance you travel is decided on your hardest days." - Futurist Jim Carroll
Your worst days will define your best days.
Your biggest mistakes make for your greatest successes.
The moments in which you seem you can barely give it enough will lead you to giving it everything you’ve got.
When it seems everything you are doing can’t make things right, you’ll suddenly find a way.
Those days in which you don’t seem to think you have enough in your tank are quietly recharging your batteries.
Do you sense a theme here?
When I talk about innovation, I constantly point out that the greatest innovators all shared something in common — they failed their way to success.
They got to the top by scraping along the bottom for a time. They only saw wonderful final results after a series of terrible, awful results.
So when those moments of quiet desperation hit, do what everyone has done: pick yourself up, shake it off, and keep moving. because things always come to those who put in the work.
Because the distance you travel is decided on those very days.
(Oh, and before you ask — no, there isn’t anything wrong here! This is just the thought that came to my head as I started my day today!)
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Futurist Jim Carroll often shares, in his keynotes, stories of successful failure.
#Distance #HardDays #Resilience #Perseverance #Failure #Success #Innovation #Strength #Journey #Determination #Grit #Motivation #Growth #Persistence #Mindset #KeepMoving #Lessons #Courage #Work #Struggle #Breakthrough #Inspiration #Rise #Effort #Onwards
Original post: https://jimcarroll.com/2026/03/daily-inspiration-the-distance-you-travel-is-decided-on-your-hardest-days/
"¿Alguna vez te has sentido como si tu cerebro estuviera en una fiesta y no estuvieras invitado? Los estudios recientes muestran que las personas con ADHD pueden experimentar 'episodios de sueño' incluso cuando están despiertas. ¿Qué nos puede decir esto sobre nuestra capacidad para enfocarnos? La respuesta puede estar en la forma en que nuestro cerebro procesa la atención. #Neurociencia #Resiliencia #Grit"
https://www.sciencedaily.com/releases/2026/03/260317015928.htm
Researchers have identified a surprising brain pattern that may help explain why people with ADHD often struggle to stay focused. Even while awake, their brains can slip into brief episodes of “sleep-like” activity during demanding tasks. These moments are linked to more mistakes, slower reaction times, and lapses in attention.
¡Excelente noticia! La investigación sobre psicodelia está avanzando rápidamente. ¿Sabías que las combinaciones de psicodelia con otras terapias pueden aumentar la eficacia y reducir los efectos secundarios? Esto nos trae un paso más cerca de superar la depresión y el estrés. ¡Es hora de explorar estas oportunidades de tratamiento innovadoras en nuestras vidas cotidianas!
Vancouver, Canada, March 17, 2026 (GLOBE NEWSWIRE) -- Clearmind Medicine Inc. (Nasdaq: CMND) (“Clearmind” or the "Company"), a clinical-stage biotech...
The resilience of young people - the ability to manage challenges and adversity in life - grows when they feel seen, safe, heard, and supported.
#Resilience #Adversity #CopingSkills #Grit #Wellbeing #CopingStrategies #Courage #Challenges #StrengthBased #MentalHealth #YMHC
"¿Sabías que hacer birdwatching puede ayudar a proteger tu cerebro de la declinación con el tiempo? Reciente investigación sugiere que pasar tiempo en la naturaleza y observar las aves puede ayudar a mantener la mente activa y flexible. ¡Así que deja de lado el libro de crossword y saca tu binoculars para descubrir el mundo desde un nuevo ángulo! #Neurociencia #Resiliencia #Grit"
https://www.sciencealert.com/birdwatching-may-help-protect-your-brain-from-age-related-decline
"¡La actividad física cambia la estructura cerebral del trauma! Recientemente se descubrió que el ejercicio regular puede reorganizar el cerebro de personas que han experimentado trauma. Esto significa que la actividad física puede ayudarnos a cambiar nuestra respuesta al estrés y a mejorar nuestra resiliencia. ¡Incluye ejercicio en tu rutina diaria y comienza a transformar tu cerebro!" #Neurociencia #Resiliencia #Grit
https://neurosciencenews.com/physical-activity-trauma-resilience-30335/
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Susana Resiste
Futurist Jim Carroll
Youth Mental Health Canada
