📌 Más recursos: cancergrace.org/forum
Agradecemos a nuestros patrocinadores por hacerlo posible: #janssen #takeda #genentech #bms #daiichisankyo

#Genentech employee shuttle: here’s what we do, here’s our podcast

#Apple / #Google shuttles: run silent run deep, please don’t egg us

I keep reading about the great job report, but I am tired of it. My son has been trying forever to get a job. He has a Master's in Biology, and that apparently isn't good enough. I am so frustrated for him. He interviews constantly, but just ... reasons. Ideally, he would love to work with Fish and Wildlife. Or Genentech. But I think at this point he just wants a job.

#fediwork #biology #fishandwildlife #genentech

🔍 Explore Advanced Data Visualization Techniques!

👨‍💻 Presented by Daniel Sjoberg, Software Engineer at Genentech, our latest webinar on "Visualizing Survival Data with the ggsurvfit R Package" is now available. Perfect for those who love digging deep into data with R!

🎥 Stream it here: https://www.r-consortium.org/r-medicine-webinar-visualizing-survival-data-with-the-ggsurvfit-r-package

#RStats #DataScience #Webinar #Genentech #ggsurvfit

R/Medicine Webinar: Visualizing Survival Data with the {ggsurvfit} R Package  - R Consortium

R/Medicine Webinar: Visualizing Survival Data with the {ggsurvfit} R Package This webinar focused on the {ggsurvfit} R package, a tool designed to simplify the creation of time-to-event or survival analysis...

R Consortium
http://bit.ly/3H1BGIT
Yesterday, The #Stanford Daily
echoed Dec.18 retraction of paper by its former president Marc Tessier-Lavigne pub in journal #Nature in 2009
Since 2012 it has been known that its claimed groundbreaking finding about #Alzheimer's disease was a fraud that boosted #GenenTech stock
Blockbuster Alzheimer’s paper retracted by former Stanford president after a decade of resistance

A 2009 study, cited as a “key scientific discovery” by Genentech as it sought a higher valuation, has now been retracted by former University head Marc Tessier-Lavigne. It is his fourth retraction in as many months.

The Stanford Daily

"In 2009, Marc Tessier-Lavigne, then a top executive at the biotechnology company #Genentech, was the primary author of a #scientific paper published in the prestigious journal Nature that claimed to have found the potential cause for brain degeneration in #Alzheimer’s patients.
[…] Neither a correction nor a retraction was issued, and the paper stands to this day."

Impressive investigation by #TheoBaker: https://stanforddaily.com/2023/02/17/internal-review-found-falsified-data-in-stanford-presidents-alzheimers-research-colleagues-allege/ #medicines #authorship #science #historyOfScience #ethics 🧶

Internal review found ‘falsified data’ in Stanford President’s Alzheimer’s research, colleagues allege

His paper was called “the miracle result.” But it never turned into an Alzheimer’s treatment. Now, four former Genentech senior scientists and executives allege that an internal review in 2011 discovered the paper had been based on fabricated research — and that Marc Tessier-Lavigne kept the results of the review from becoming public. He denies the allegations.

The Stanford Daily

My latest clinical pipeline column for @NatureMedicine is out today.
It's a look at the recent approval of mosunetuzumab, #Genentech's bispecific anti CD20/CD3 monoclonal antibody
for relapsed or refractory follicular #lymphoma.

#FollicularLymphoma #Hematology #MonoclonalAntibody #DrugDevelopment

https://www.nature.com/articles/d41591-023-00010-0

FDA approves Genentech’s bispecific antibody for lymphoma

Nature Medicine explores the latest translational and clinical research news, with data from an ongoing clinical trial of mosunetuzumab in relapsed or refractory follicular lymphoma.

#COVID NEWS (USA)

#FDA approved a new indication for the #monoclonal #antibody tocilizumab (Actemra, #Genentech) for treatment of hospitalized adults with #COVID19 receiving systemic corticosteroids and requiring supplement oxygen, mechanical ventilation (invasive or non-invasive), or #ECMO.

https://www.fda.gov/media/150319/download

Robert Swanson was born on this day in 1947. Swanson was one of the founders of Genentech, the first company dedicated to genetic engineering.

#ThisDayInBiotech #Biotechnology #Biotech #RobertSwanson #Genentech #GENE

Hot off the press: in vivo active SMARCA2 degraders, courtesy of a joint effort between my #Arvinas colleagues and collaborators at #Genentech.
https://www.nature.com/articles/s41467-022-34562-5
Selective PROTAC-mediated degradation of SMARCA2 is efficacious in SMARCA4 mutant cancers - Nature Communications

SMARCA2 has been identified as a synthetic lethal target in SMARCA4 mutated tumors, however, homology between the two has hindered the development of selective SMARCA2 inhibitors. Here, the authors synthesize a proteolysis targeting chimera (PROTAC) capable of SMARCA2 specific degradation and demonstrate its utility in the treatment of SMARCA4 mutated tumors.

Nature