📰 Happy to announce the publication in @PeerCommunityJournal of our analysis of #VaginalMicrobiota dynamics.

🦠 This work provides unprecedented insights into the occurrence of #dysbioses.

Thanks to the #women participating in the #PAPCLEAR study at CHU Montpellier (France) 🙏

The model (all in #RStan) was built by @tsukushi_kamiya and the #16S sequencing of over 2.000 samples was done in Jacques Ravel's lab. This work stems from the @ERC_Research #EVOLPROOF project.

https://peercommunityjournal.org/articles/10.24072/pcjournal.527/

Factors shaping vaginal microbiota long-term community dynamics in young adult women

4 years of clinical study, 4 years of analyses: we are proud to see the results of the #PAPCLEAR study deciphering the #dynamics of #papillomavirus genital infections 🦠 in young women is published in @PLOSBiology

https://doi.org/10.1371/journal.pbio.3002949

A huge 🙏 to the study participants, the clinical staff of the CEGIDD at #CHU_Montpellier 🏥 , the @ERC_Research for funding, and all the @ete and @EcoEvoHealth team in the dry and wet labs! 🔬

@cnrs #UMontpellier #IRD #MIVEGEC #EVOLPROOF #HPV @CirbCdf

Viral and immune dynamics of genital human papillomavirus infections in young women with high temporal resolution

Human papillomavirus (HPV) infections drive one in twenty new cancer cases, with a particular burden on women. This analysis of longitudinal clinical data using kinetics models reveals that HPV infections exhibit a long plateau virus load and that their clearance is associated with specific signals in the host immune response.

Congratulations to Thomas Beneteau for his in-depth analysis of the #incidence and #duration of #HPV infections in young women using multivariate #Cox regression models with #frailty effects.

This work based on the #PAPCLEAR #cohort in #Montpellier and the #EVOLPROOF project is now published in #InfectiousDiseases.

#DM for a #PDF version until we can opt for #GreenOpenAccess.

https://doi.org/10.1080/23744235.2024.2427223

We thank all the #participants of the #PAPCLEAR study for their commitment, and all the staff of the #CEGIDD of #Montpellier for their help! 🙏

This study was supported by @[email protected] #EVOLPROOF, the #ARNS-MIE, @[email protected], and @[email protected] .

https://www.inee.cnrs.fr/fr/cnrsinfo/comparaison-des-profils-immunitaires-entre-coupes-menstruelles-et-tampons

8/N

Comparaison des profils immunitaires entre coupes menstruelles et tampons

Une récente étude clinique sur les infections sexuellement transmissibles chez les jeunes femmes a permis d’étudier des différences entre utilisat

INEE

Nous remercions toutes les #participantes de l'étude #PAPCLEAR pour leur engagement, et tout le personnel du #CeGIDD de #Montpellier pour leur aide !

Cette étude a été soutenue par l'#ERC #EVOLPROOF, par l'#ARNS-MIE, le #CNRS et le #CHU de #Montpellier.

https://www.inee.cnrs.fr/fr/cnrsinfo/comparaison-des-profils-immunitaires-entre-coupes-menstruelles-et-tampons

8/N

Comparaison des profils immunitaires entre coupes menstruelles et tampons

Une récente étude clinique sur les infections sexuellement transmissibles chez les jeunes femmes a permis d’étudier des différences entre utilisat

INEE

We thank all the #participants of the #PAPCLEAR study for their commitment, and all the staff of the #CEGIDD of #Montpellier for their help!

This study was supported by the #ERC #EVOLPROOF, by the #ARNS-MIE, the #CNRS, and the #CHU of #Montpellier.

https://www.inee.cnrs.fr/fr/cnrsinfo/comparaison-des-profils-immunitaires-entre-coupes-menstruelles-et-tampons

8/N

Comparaison des profils immunitaires entre coupes menstruelles et tampons

Une récente étude clinique sur les infections sexuellement transmissibles chez les jeunes femmes a permis d’étudier des différences entre utilisat

INEE