The EMBO JournalJan 12, 2024
Why is functional #autophagy important for #cardiac health?
Abel Lab and collaborators shows that #autophagic flux controls NAD+ homeostasis in #cardiomyocytes, thereby preventing #mitochondrial dysfunction
https://www.embopress.org/doi/full/10.1038/s44318-023-00009-w
jobRxivJan 1, 2024

Graduate Research Assistant

Florida State University

The Solis lab at @FloridaState has PhD assistantships to studying the #mechanobiology of #cardiomyocytes #MyoTwitter https://solislab.create.fsu.edu/

See the full job description on jobRxiv: https://jobrxiv.org/job/florida-state-university-27778-graduate-research-assistant/?feed_id=68985

#bioengineering #biomedical #biophysics #cardiomyocy...
https://jobrxiv.org/job/florida-state-university-27778-graduate-research-assistant/?feed_id=68985

The Solis Lab – Just another WordPress site

jobRxivNov 30, 2023

Graduate Research Assistant

Florida State University

The Solis lab at @FloridaState has PhD assistantships to studying the #mechanobiology of #cardiomyocytes #MyoTwitter https://solislab.create.fsu.edu/

See the full job description on jobRxiv: https://jobrxiv.org/job/florida-state-university-27778-graduate-research-assistant/?feed_id=66605

#ScienceJobs #hiring #research
Tallahassee, Florid...
https://jobrxiv.org/job/florida-state-university-27778-graduate-research-assistant/?feed_id=66605

The Solis Lab – Just another WordPress site

GonzaloFeb 7, 2023

Just Published!

"Direct Cardiac Reprogramming: Current Status and Future Prospects"

https://link.springer.com/chapter/10.1007/5584_2022_760

#Cardiomyocytes #CardiovascularDiseases
#CellTherapy #CardiacReprogramming #CellBiology

Direct Cardiac Reprogramming: Current Status and Future Prospects

Advances in cellular reprogramming articulated the path for direct cardiac lineage conversion, bypassing the pluripotent state. Direct cardiac reprogramming attracts major attention because of the low or nil regenerative ability of cardiomyocytes, resulting in...

SpringerLink
Gal Haimovich πŸ˜·πŸ”¬β˜£πŸ³οΈβ€πŸŒˆπŸ³οΈβ€βš§Jan 5, 2023

This is neat!
A paper in @eLife from Anne-Catherine Prats lab (U Toulouse) looking at #IRES regulation.
They show that #mRNA with IRES in #cardiomyocytes interactes with #lncRNA NEAT1 in nuclear paraspeckles, and suggest an assembly of an "IRESome" -with paraspeckle-related proteins - that regulates IRES-dependent translation (here - upon hypoxia).

https://elifesciences.org/articles/69162

Long non-coding RNA Neat1 and paraspeckle components are translational regulators in hypoxia

LncRNA Neat1, with paraspeckle proteins, controls translational induction of (lymph)angiogenic and cardioprotective factors by the IRES-dependent mechanism in mouse cardiomyocytes submitted to hypoxia.

eLife
Alessandro BerteroDec 12, 2022

A novel study we contributed to provides the first detailed analysis of 3D #chromatin organisation changes during the development of #endothelium, and how they correlate with gene expression regulations. The study also compares these dynamics with those we previously reported for #cardiomyocytes. Kudos Kris and Katie for spearheading this work! #UW #ISCRM #4DNucleome

https://www.cell.com/stem-cell-reports/fulltext/S2213-6711(22)00536-7