AI-Analyzed Mammograms Assess Your Heart: Women with abundant breast arterial calcium nearly 3x likely to die from cardiac disease over 5 years. #mammogram #calcification #breast #arteries #cardiovascular #stroke
https://www.instagram.com/drhowardsmithreports/reel/DH9SFeIs78Z/
Howard G. Smith MD, AM on Instagram: "AI-Analyzed Mammograms Assess Your Heart Women under 60 years of age with the most significant calcium buildup in their breast arteries, compared with those who had the least, were 2.8 times more likely to die from cardiac disease within a 5 year period. This from an Emory University and Mayo Clinic collaborative study of 56,000 mammograms presented at the American College of Cardiology's Annual Scientific Session. Visualizing calcium plaques in breast arteries seen on cancer-screening mammograms can incidentally predict cardiovascular disease. Other studies have shown that such calcium deposition in the breast arteries breast arteries is associated with a 51% higher risk of not only heart disease but also stroke. The AI model looked at the severity of breast artery calcification and divided women into 3 groups. Then it analyzed the incidence of heart attack, heart failure, and stroke for each group. Greater levels of calcification was associated with risk of these diseases for all women 80 years and younger. Once additional confirmation and verification studies are complete, they will be presented to the FDA for approval. With that, multi-purposing of mammography will find its way into the clinic…….someday soon. https://medicalxpress.com/news/2025-03-ai-powered-mammograms-window-heart.html #mammogram #calcification #breast #arteries #cardiovascular #stroke"

0 likes, 0 comments - drhowardsmithreports on April 2, 2025: "AI-Analyzed Mammograms Assess Your Heart Women under 60 years of age with the most significant calcium buildup in their breast arteries, compared with those who had the least, were 2.8 times more likely to die from cardiac disease within a 5 year period. This from an Emory University and Mayo Clinic collaborative study of 56,000 mammograms presented at the American College of Cardiology's Annual Scientific Session. Visualizing calcium plaques in breast arteries seen on cancer-screening mammograms can incidentally predict cardiovascular disease. Other studies have shown that such calcium deposition in the breast arteries breast arteries is associated with a 51% higher risk of not only heart disease but also stroke. The AI model looked at the severity of breast artery calcification and divided women into 3 groups. Then it analyzed the incidence of heart attack, heart failure, and stroke for each group. Greater levels of calcification was associated with risk of these diseases for all women 80 years and younger. Once additional confirmation and verification studies are complete, they will be presented to the FDA for approval. With that, multi-purposing of mammography will find its way into the clinic…….someday soon. https://medicalxpress.com/news/2025-03-ai-powered-mammograms-window-heart.html #mammogram #calcification #breast #arteries #cardiovascular #stroke".

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Journal of Materials Science: Materials in Medicine

SpringerLink
Heavy metal exposure could increase cardiovascular disease risk, study finds

Exposure to heavy metals may increase risk of calcium buildup in the walls of coronary arteries, which can lead to chronically narrowed arteries, a new study found.

CNN
Looking for numbers on community #calcification rate. It seems the literature has only two options "#reef" (shallow, corals) or "#plankton"...
Temperate reefs? #Mesophotic reefs? Calcareous algae meadows? #Seagrass epiphytes? Sorry, nothing for you.
#Artery #calcification, or atherosclerosis as it is also known, involves #fatty deposits accumulating on the inside of the #arteries, making it harder for #blood to pass through.
#Medical #sflorg
https://www.sflorg.com/2023/12/med12212301.html
Artery calcification more common in night owls

Artery calcification is almost twice as common in night owls compared to early birds

#ClimateCrisis: #OceanAcidification in the #Mediterranean is already affecting the #calcification of marine #plankton https://phys.org/news/2023-11-ocean-acidification-mediterranean-affecting-calcification.html paper: https://www.nature.com/articles/s43247-023-00947-7

"#Foraminifera #protists... build a shell, several hundred micrometers in size, which is made of #CalciumCarbonate... these #calcite structures are highly sensitive to changes in seawater #chemistry... This is reflected in an accelerated decrease in shell weight during the 20th century."

Study concludes ocean acidification in the Mediterranean is already affecting the calcification of marine plankton

The acidification of the oceans caused by human activity is already altering the production of marine plankton shells in the Mediterranean Sea. This is the worrying conclusion of a study led by the Institute of Environmental Science and Technology of the Universitat Autònoma de Barcelona (ICTA-UAB), which raises concerns about the impact the decrease in pH of the surface ocean has on the production of calcium carbonate by marine plankton and its negative consequences for marine ecosystems.

Phys.org
New pathway of diatom-mediated calcification and its impact on the biological pump

A research team found that the photosynthesis of Skeletonema costatum (S. costatum), a common diatom species, can induce substantial aragonite precipitation from artificial/natural seawater under significantly lower supersaturation levels required for the precipitation of inorganic CaCO3.

Phys.org
After a hiatus for #ReC2301, back to #WeekendReading: Pallacks et al. on how acidification in the western #Mediterranean impacts biogenic #calcification (as usual, things are more complicated in the eastern basin - I should get around to work on that).
https://www.nature.com/articles/s43247-023-00947-7
Anthropogenic acidification of surface waters drives decreased biogenic calcification in the Mediterranean Sea - Communications Earth & Environment

Increasing atmospheric concentrations of anthropogenic carbon dioxide and acidification of surface waters have led to basin wide reductions in planktic foraminifera calcification in the Mediterranean Sea, suggest sediment core analyses of shell weight, geochemistry, and supporting proxies.

Nature

Excellent editorial on the potential role of #magnesium in vascular #calcification in #CKD.

Nicely explains why measuring serum levels of magnesium is not sufficient and which hardships exist in estimating total magnesium levels.

#Nephrology

https://academic.oup.com/ndt/advance-article/doi/10.1093/ndt/gfad059/7091935

Magnesium: extracellular, intracellular or total magnesium status?

Observational studies in hemodialysis patients describe a negative association between magnesium body stores and all-cause and cardiovascular mortality [1]. In

OUP Academic

Here's a transmission electron microscopy (TEM) image of #bone showing mineralized #collagen and an #osteocyte lacuna containing microcalcifications of #apatite and #whitlockite.

Such #calcification or #mineral formation is part of normal physiological processes such as #apoptosis but can also indicate #pathology.

The specimen was prepared using focussed ion beam scanning electron microscopy (FIB-SEM).

Read more:
https://pubs.acs.org/doi/abs/10.1021/acs.nanolett.7b02888

#ThinSectionThursday #Biomaterials #ElectronMicroscopy