"Sign up for SO MANY OBLIGATIONS. THIS! ENERGY! WON'T! FADE!"

Ok. First of all, how dare you.

#MentalHealth #bpi #bpii #bp1 #bp2 #BiPolar

Kanye's #bipolar apology letter checks out.

https://www.theguardian.com/music/2026/jan/26/kanye-west-takes-out-full-page-ad-apologising-for-antisemitic-behaviour-and-denying-he-is-a-nazi-ye

Specifically I mean that his letter makes accurate claims about bipolar disorder. I live with bipolar type 2 #BP2 myself (as well as #AuDHD and #CPTSD).

Bipolar can make you obsess over topics you don't normally think about and act on values and beliefs you don't even hold.

Bipolar can make you behave in ways that are profoundly at odds with your values.

Bipolar isn't exclusively inherited and it can be triggered by stressful life experiences, like brain injury.

Some psychiatrists hold that some cases of bipolar are better understood as a recurring pattern of autistic burnout. We don't have much research or clinical experience on how bipolar and autism interact.

Many people have observed that Kanye has a new album pending release and see this apology as a PR endeavour.

Many people, including me, think Kanye is, at a bare minimum, kind of a jackass.

But while I've never released a Nazi anthem and merch, I absolutely believe that could have been the bipolar talking. I don't believe he is trying to 'blame bipolar' for behaviour and beliefs that were really his own.

I call bipolar 'the dickhead disease' because hypomania is overconfidence on steroids and mania is that plus very energetic obsession.

Mania is a psychotic state. You lose touch with reality, but you also lose touch with yourself — you have no insight into what's happening and your lifelong values seem meaningless.

So I appreciate people saying with the best of intentions that bipolar doesn't make you a Nazi — but when Kanye says it did in his case, I believe him.

Kanye West takes out full-page ad apologising for antisemitic behaviour and denying he is a Nazi

Rapper, now known as Ye, apologises to his family and to the Black community and says he loves Jews, blaming his bipolar disorder for his ‘poor judgment and reckless behaviour’

The Guardian
Identification of Bacterial FtsZ Effectors Targeting the Sites of Coumarin Binding - Cytology and Genetics

Abstract— There is a large group of bacterial FtsZ inhibitors, the biological activity of which has been confirmed biochemically. However, the sites of protein-ligand interaction for most of them remain unknown, significantly complicating the further search and combinatorial design of FtsZ inhibitors. This study presents the results of bioinformatic analysis of bacterial FtsZ effectors targeting sites of 4-hydroxycoumarin binding (BP1 and BP2). New data based on original results of pharmacophore screening, chemoinformatics, molecular docking, molecular dynamics simulations, AI-predictions, etc., are presented. The object of the study was a combined library of 379 compounds, formed based on revision of the structural database RCSB Protein Data Bank and biochemically proven FtsZ effectors from ChEMBL. Based on the results of a comprehensive study, 39 compounds were selected, of which 28 were identified as effectors of the sites BP1 and BP2, and another 11 as specific effectors of the site BP2 located in the BP2/IDC superpocket.

SpringerLink
Yeah, I def woke up mildly hypomanic again. So I took another half-dose of the anti-mania medication, pulled on my boots and went on a round trip of the Inner West, getting refunds and exchanges for faulty Wiz bulbs at Bunnings, (thank fuck nearby Victoria's Basement was closed or I WOULD have bought more kitchen gadgets), bought coffee and bread at BSB, picked up fresh fruit and vegies at Panetta, also some lamb shanks at the Metro, and then walked home in the sunshine. All of that in two hours. Like I said, hypo. And probs gonna pay for it when the ride is over. #bp2

@TexasObserver

>On this particular day last year, she feared leaving the shower because she thought someone was trying to harm her. She hears voices and sees imaginary people. The officer on duty tried to calm her down. Her mental health counselors tried to persuade her that no one was out there or going to harm her. To no avail.
>
>After about an hour of trying to get Timmons out of the shower, Senior Warden Audrey England seemed frustrated. ...
>
>“Get this dumba** out of here! Run a team,” I thought I heard the warden say.
>
>“Run a team” means suit up for combat. The team, which were mainly male officers, raced into the shower where the woman in crisis was naked. They were carrying Tasers and batons and after deploying those weapons left her on the floor, cooking like a steak on a grill. It was the first time I saw or heard a Taser used in prison.
>
>After hours of being left on the shower floor, Timmons was hogtied with shackles and dragged to her cell naked by male officers. Burn marks could be seen where the prongs from the Tasers roasted her skin. The smell of seared flesh filled the air.

The cruelty is the point. If Timmons was going to be left in the showers for hours anyway, why bother deploying tasers or a team on her in the first place? I want to say that a psych ward is a better place for addressing mental illness, but having been involuntarily committed before myself, the similarities between a ward and and a prison are too uncanny to ignore.

#CriminalJustice #bipolar #bp2 #MentalHealth

I had developed a hunch that Wegovy was affecting the uptake of my #BP2 medication. In most people it causes constipation but in me, very much the opposite. So I increased my dose of Abilify a notch last night and hey presto I feel a LOT calmer this morning.

What a weird life I lead, like a little biochemical cyborg, locked in a set of feedback loops with my medication. Medication goes up, mood comes down. Mood comes down too much, medication comes down a little too. Repeat.

But I am grateful I am living in these times as earlier treatments for bipolar 1 were horrendous and they didn't even recognise that #BP2 existed yet.

I was quite worried yesterday that I was seeing the early warning signs of hypomania.

Then I went to take my meds last night and remembered that I ran out of the really key one a night ago.

That'll do it...

And it is giving me a ferocious headache now 😖 I am waiting out the 2h until my chemist opens and I can fix it!

#bp2

Hot damn it's warm out there.

I have had a productive morning though!

Brekkie at the café, dentist for a clean, haircut, fresh groceries, sunny walk home.

Chilling out for a bit then I want to make some tadka dal and recipe test the grilled cos salad I'm making for dinner with a friend.

The GLP-1 inhibitor has definitely given me some energy and emotion back. I have to keep a close eye on this as energy and emotion can signal the onset of hypomania in #bp2. But in the short term it's nice to feel things intensely once more!

When my friends talked about the hyperemesis they experienced upon starting Wegovy, I had a hunch from the timings they described that it might be due to food sitting in place for too long.

I got the chance to put that to the test when I started taking it recently myself.

Although this is n=1 anecdote, taking a product containing hyoscine / atropine / hyoscamine — anti-emetics which encourage the stomach to relax and empty its contents — does seem to reduce nausea/vomiting.

This is a useful one to know because the other anti-emetics (stemetil and Zofran) are both brain meds and people like me can't take them without fear of triggering an episode of #bp2-related hypo/mania.

Ughhhh I've had the bad feels all day. Anxiety and sadness and PDA. I have done good things for it (eaten, took meds) and bad things for it (caffeinated too much). I need to tidy but it's just going to have to wait. I get 1-2x days like this per fortnight and I just have to ride them out. #bp2