Christopher Chase Bolt

@cchaseb
30 Followers
172 Following
47 Posts

I’m enthusiastic about genomes, the chromatin ecosystem, and genome engineering problems.

Formerly a Swiss-living postdoc, now Boston-side biotech.

he/him

ORCiD0000-0002-3544-3552

A breathtaking piece of work on vertebrate fertilization receptors. Really beautiful. Congrats to all involved. 🧪

https://www.cell.com/cell/fulltext/S0092-8674(24)01093-6?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0092867424010936%3Fshowall%3Dtrue

Disturbed #gut flora during the first years of life is associated with diagnoses such as #autism and #ADHD later in life. The study is the first forward-looking, or prospective, study to examine gut flora composition and a large variety of other factors in #infants, in relation to the development of the children's #nervous system.
#Microbiology #Biomedical #Neuroscience #Psychiatry #sflorg
https://www.sflorg.com/2024/04/mcb04042401.html
Autism and ADHD are linked to disturbed gut flora very early in life

The present study also confirms that the risk of developmental neurological diagnosis

The impact of intermittent fasting

Intermittent fasting triggers the release of the protein IL-22 in specific gut immune cells, which results in beigeing of white fat cells to improve energy use.

eLife Sciences Publications, Ltd
Bacterial ligases reveal fundamental principles of polyubiquitin specificity https://www.cell.com/molecular-cell/fulltext/S1097-2765(23)00962-0?rss=yes&utm_source=dlvr.it&utm_medium=mastodon
m6A modification negatively regulates translation by switching mRNA from polysome to P-body via IGF2BP3 https://www.cell.com/molecular-cell/fulltext/S1097-2765(23)00911-5?rss=yes&utm_source=dlvr.it&utm_medium=mastodon

Between my commuter rail line shuttling half the stops and there being 10min headways on both the Orange and Red lines at 5:15PM today I’m just gonna stop referring to the #MBTA as transit.

It’s just one of those rusty temporary theme park rides that your city sets up in a parking lot somewhere around the 4th of July.

Great to see this out- ABC was a great resource but this looks even better- was super interested to hear about it at #EMBOenhanceropathies a couple of weeks back #enhancers #generegulation https://www.biorxiv.org/content/10.1101/2023.11.09.563812v1
The way that leftist organizations are supporting Hamas will cause the greatest shift right in a generation.
Once upon a time (in my lifetime) people thought it was a good idea to put carpet in bathrooms.
Is there an internal policy at Apple to hide everything behind little menus 💩?