Ariel K. Frame

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30 Posts
BSc Biology || PhD Neuroscience || Postdoc with Andrew Lin at University of Sheffield || Drosophila, aging, learning and memory, neurobiology. Host: linktr.ee/quitecurious bit.ly/ArielFrame_GoogleScholar
First episode of my podcast is out! I spoke with Professor James Marshall
at University of Sheffield about his research on modelling the #brain of #bees and implications for #ai. Take a listen! #neuroscience #sciencecommunication
Check out this summary of the split-GAL4 method development over the past 10 years. Good resource. https://www.biorxiv.org/content/10.1101/2024.01.09.574419v1
After plenty of nurturing, my #preprint baby has now matured into a fully formed publication in Aging. https://doi.org/10.18632/aging.204565 This #Drosophila study on #lactate #brainmetabolism, #Aging and #Memory is my first paper including data from my PhD thesis. I’ve got a couple more papers up my sleeve before I graduate this summer. Keeping my eyes out for #postdoc positions studying aging and behaviour in flies.
Aging and memory are altered by genetically manipulating lactate dehydrogenase in the neurons or glia of flies | Aging

Aging | doi:10.18632/aging.204565. Ariel K. Frame, J. Wesley Robinson, Nader H. Mahmoudzadeh, Jason M. Tennessen, Anne F. Simon, Robert C. Cumming

Since there have been published methods describing how to do it successfully with flies, has anyone adopted cryopreservation for any of their lab stocks? Why or why not? e.g. https://www.nature.com/articles/s41467-021-22694-z I am waiting for the day frozen fly stocks become as easily maintained as C. elegans are.
Cryopreservation method for Drosophila melanogaster embryos - Nature Communications

The development of a widely adopted cryopreservation method remains a major challenge in Drosophila melanogaster research. Here the authors report a robust cryopreservation protocol of Drosophila embryos and showcase its implementation in 25 distinct strains from different sources.

Nature