Mastodawn

Mill_lab Jan 16, 2024

Then the high point of #ukcilia2024 e-symposia our breakout panel discussions- talk of #cilia synapses, 'not all cilia have equal opportunity for signaling' and connections and how they evolve, and more... 7/8

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Mill_lab Jan 16, 2024

We close with Dan Dodd (Mill lab, MRC HGU) on unique #cilia & #centriole-specific functions for #tubulin isotype TUBB4B with dominant negative roles in motile & non-motile #ciliopathies. New insights from Alan Brown & Jeff Ti Labs. Deep read: www.medrxiv.org/content/10.1... #ukcilia2024 6/8

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Mill_lab Jan 16, 2024

#Mouse genetics reveal different neuron-specific #cilia functions to different #drugs via GPCRs to drive motivated behaviours Jeremy McIntyre (U Florida). Deep read: https://journals.sagepub.com/doi/10.1177/02698811231219058 #ukcilia2024 5/8

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Mill_lab Jan 16, 2024

Part II Saikat Mukhopadhyay (UTSW) on mechanism of #cilia disassembly as cells migrate during differentiation- partial loss of cilia maintenance gene expression programme in cerebellar granular neurons- no PCM, no satellites but centrioles intact! https://www.biorxiv.org/content/10.1101/2023.12.07.565993v1 #ukcilia2024 4/8

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Mill_lab Jan 16, 2024

Then a double billing of curious roles for #cilia disassembly in cerebellar granular neuron differentiation using #volumetricEM to map changes in structure- tour-de-force talk by Carolyn Ott (JLS lab, HHMI Janelia). Must read pre-print 1: https://www.biorxiv.org/content/10.1101/2023.12.07.565988v1 #ukcilia2024 3/8

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Mill_lab Jan 16, 2024

On to beta islet cell #cilia in stunning FIB-SEM vEM from human & mouse pancreas. Masterclass talk by Andreas Müller (Solimena lab, TU Dresden) with Nikolai Klena Gaia Pigino with incredible cellular connections & signal exposure! https://www.biorxiv.org/content/10.1101/2023.12.01.568979v4 #ukcilia2024 2/8

Mill_lab Jan 16, 2024

We kicked off our 46th BSCB GenSoc UK Cilia Network e-symposium with newly minted Dr Dheeraj Rayamajhi (Roy lab, A*STAR, SG)- conserved roles for FOXJ1 in ciliated olfactory sensory neurons without motile transcriptional signatures. Intriguing questions about mechanisms- a co-repressor? ICYMI: https://www.biorxiv.org/content/10.1101/2023.05.10.540158v1 1/8

Mill_lab Jan 15, 2024

Our 46th BSCB GenSoc UK Cilia Network e-symposium tomorrow 16/01/2024 15:00-17:30 GMT online will be 🔥: #cilia on beta cells, NEURONS NEURONS NEURONS 🧠 & in rare disease- come here more about #cilia in (tissue) space and complex connections revealed by volumetric TEM! Free and open to all register once here! https://www.eventbrite.co.uk/e/bscb-gensoc-uk-cilia-network-e-symposia-series-tickets-122092125835?aff=oddtdtcreator

BSCB GenSoc UK Cilia Network e-Symposia Series

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Mill_lab Sep 4, 2023

⚠️End of play today ⚠️ is the deadline for submitting an abstract to be considered for a talk and/or poster for our inperson UK Cilia Network Fall Meeting https://forms.office.com/e/EtTDAeGaFY

🎇Great opportunity for #cilia & #centrosome students, postdocs & #newPIs to give a podium talk!🎇

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Mill_lab Sep 1, 2023

Two+ weeks 🚨 19/09/2023 15:00-17:15 BST 🚨until our 45th BSCB GenSoc UK Cilia Network e-symposium- free and open to all! >1260 folks already registered, this is the #cilia #centriole place to be! Not on my list already, sign up here: https://www.eventbrite.co.uk/e/bscb-gensoc-uk-cilia-network-e-symposia-series-tickets-122092125835

We have all good things lined-up: #GeneRegulatoryNetworks, #Signalling, mind-blowing #cryoET protein ID, #OrganelleProteomics in #neurons AND everything #tubulin! Join us...

BSCB GenSoc UK Cilia Network e-Symposia Series

Eventbrite

Lab website:	https://www.cilialab.co.uk/
Uni website:	https://www.ed.ac.uk/mrc-human-genetics-unit/research/mill-group
ORCID:	0000-0001-5218-134X