(1/2) Very happy to announce the publication of our latest work by my former student Sylvain Pouzet in @journal-evo.bsky.social: "Gene network topology drives the mutational landscape of gene expression". Based on simulations, we show that the size and pleiotropy of mutations affecting gene expression heavily depend on the structure of the underlying gene network.

#GeneRegulatoryNetworks
#PopulationGenetics
#EvolutionarySystemsBiology

https://doi.org/10.1093/evolut/qpaf068

Two+ weeks 🚨 19/09/2023 15:00-17:15 BST 🚨until our 45th BSCB GenSoc UK Cilia Network e-symposium- free and open to all! >1260 folks already registered, this is the #cilia #centriole place to be! Not on my list already, sign up here: https://www.eventbrite.co.uk/e/bscb-gensoc-uk-cilia-network-e-symposia-series-tickets-122092125835

We have all good things lined-up: #GeneRegulatoryNetworks, #Signalling, mind-blowing #cryoET protein ID, #OrganelleProteomics in #neurons AND everything #tubulin! Join us...

#Conference — only two weeks to go until our #MicrobiologySociety Focus Meeting about #MicrobialEvolution in #Manchester UK 22-23 November

#ExperimentalEvolution #PathogenGenomics #Microbiome #dynamics #Mathematical #modelling #crispr #plasmids #phages #GeneRegulatoryNetworks #PredictingEvolution #EvolutionaryApplications #MutationRates #HorizontalGeneTransfer #EvolutionaryTheory #EvolutionaryInnovation #EvolutionaryRescue #EcoEvolutionaryDynamics

To register: https://microbiologysociety.org/event/full-events-listing/understanding-and-predicting-microbial-evolutionary-dynamics.html#tab-4

#introduction post! 🎉

I'm Alan, from #Ireland 🇮🇪, living in Bath 🇬🇧

I'm an #LGBTInSTEM 🏳️‍🌈 molecular #evolution 🧬 #bioinformatics 👨‍💻 #postdoc researcher, currently having a gander at #GeneRegulatoryNetworks in #Pseudomonas 🦠. I'm more interested in gene duplication than the average person.

I like #baking 🍰 and am a big fan of naps 😴. I've also recently started #archery 🎯.

A passion is #inclusive #greetingcards and I recently started posting some favs over on https://inclusive.cards.

Dia dhaoibh!

#HelloWorld, time to do my #introduction 👋

I’m a #computerScientist working as research fellow in #computationalMedicine and doing a lot of #bioinformatics and #geneticEpidemiology.

I develop and apply statistical and computational methods to identify #multiomics modifications influencing complex human phenotypes. I’ve also worked on the problem of #knowledgeDiscovery in biological data, and on the reverse engineering of #geneRegulatoryNetworks.