Mill_lab

@[email protected]
560 Followers
443 Following
503 Posts
Group at MRC HGU using #genetics, #CellBiology and lots of #imaging to unlock the mysteries of mammalian #cilia. #centrioles #cytoskeleton #RareDisease #ScienceMastodon #AcademicMastodon
Lab website:https://www.cilialab.co.uk/
Uni website:https://www.ed.ac.uk/mrc-human-genetics-unit/research/mill-group
ORCID:0000-0001-5218-134X
Mill_labMar 16, 2025
@Co_BiologistsFeb 25, 2025

Last few days to submit your research for @J_Cell_Sci upcoming special issue - Cilia and Flagella: from Basic Biology to Disease. This issue will be coordinated by two Guest Editors: Pleasantine Mill @Mill_lab (University of Edinburgh) and Lotte Pedersen (University of Copenhagen).

The deadline for submitting articles is 1 March 2025. https://journals.biologists.com/jcs/pages/cilia

Mill_labNov 15, 2024
Journal of Cell ScienceSep 13, 2024

We are now accepting papers for our Special Issue, Cilia and Flagella: from Basic Biology to Disease, coordinated by Pleasantine Mill
@Mill_lab & Lotte Pedersen. We encourage submissions of Research Articles, Short Reports, & Tools & Resources papers.

Submission deadline: 1 March 2025

https://journals.biologists.com/jcs/pages/cilia

#Cilia2024

Show threadMill_labJan 16, 2024
We had 325 folks join us today, our next @Official_BSCB @GenSocUK @UKCiliaNetwork e-symposium is 23/04/2024- if you are not already signed up, do so here: https://www.eventbrite.co.uk/e/bscb-gensoc-uk-cilia-network-e-symposia-series-tickets-122092125835?aff=oddtdtcreator free and open to all! /fin
BSCB GenSoc UK Cilia Network e-Symposia Series

BSCB GenSoc UK Cilia Network e-Symposia Series

Eventbrite
Show threadMill_labJan 16, 2024
Then the high point of #ukcilia2024 e-symposia our breakout panel discussions- talk of #cilia synapses, 'not all cilia have equal opportunity for signaling' and connections and how they evolve, and more... 7/8
Show threadMill_labJan 16, 2024
We close with Dan Dodd (Mill lab, MRC HGU) on unique #cilia & #centriole-specific functions for #tubulin isotype TUBB4B with dominant negative roles in motile & non-motile #ciliopathies. New insights from Alan Brown & Jeff Ti Labs. Deep read: www.medrxiv.org/content/10.1... #ukcilia2024 6/8
Show threadMill_labJan 16, 2024
#Mouse genetics reveal different neuron-specific #cilia functions to different #drugs via GPCRs to drive motivated behaviours Jeremy McIntyre (U Florida). Deep read: https://journals.sagepub.com/doi/10.1177/02698811231219058 #ukcilia2024 5/8
Show threadMill_labJan 16, 2024
Part II Saikat Mukhopadhyay (UTSW) on mechanism of #cilia disassembly as cells migrate during differentiation- partial loss of cilia maintenance gene expression programme in cerebellar granular neurons- no PCM, no satellites but centrioles intact! https://www.biorxiv.org/content/10.1101/2023.12.07.565993v1 #ukcilia2024 4/8
Show threadMill_labJan 16, 2024
Then a double billing of curious roles for #cilia disassembly in cerebellar granular neuron differentiation using #volumetricEM to map changes in structure- tour-de-force talk by Carolyn Ott (JLS lab, HHMI Janelia). Must read pre-print 1: https://www.biorxiv.org/content/10.1101/2023.12.07.565988v1 #ukcilia2024 3/8
Show threadMill_labJan 16, 2024
On to beta islet cell #cilia in stunning FIB-SEM vEM from human & mouse pancreas. Masterclass talk by Andreas Müller (Solimena lab, TU Dresden) with Nikolai Klena Gaia Pigino with incredible cellular connections & signal exposure! https://www.biorxiv.org/content/10.1101/2023.12.01.568979v4 #ukcilia2024 2/8
Mill_labJan 16, 2024
We kicked off our 46th BSCB GenSoc UK Cilia Network e-symposium with newly minted Dr Dheeraj Rayamajhi (Roy lab, A*STAR, SG)- conserved roles for FOXJ1 in ciliated olfactory sensory neurons without motile transcriptional signatures. Intriguing questions about mechanisms- a co-repressor? ICYMI: https://www.biorxiv.org/content/10.1101/2023.05.10.540158v1 1/8