Dr Eileen Parkes

17 Followers
136 Following
53 Posts
Cancer immunology lab, early phase trials, Oxford via Belfast, Oncologist, MD PhD, Lincoln College JRF, mum #womeninSTEM #immunology #DNAdamage All my own views
Who sets this wordiply thing anyway...
Today should be Jacinda Arden day - when every busy, stretched woman who has ever thought "I can't do this" has a full day off - no responsibilities except to do absolutely nothing, ignore deadlines and have a glorious long rest

RT @[email protected]

Extremely happy to share our last paper in @[email protected] with the community! Big team effort, congrats and a huge thank you to all authors, it was a pleasure to work with all of you on this! 🥳🥳🥳 #immunogenomics #TME #brain_metastasis https://twitter.com/johanna_a_joyce/status/1615376628317650949

🐦🔗: https://twitter.com/aalvarezprado/status/1615383584436633603

Johanna Joyce on Twitter

“How do cancer cells sculpt their tumor microenvironment??🤔 We analyzed brain metastases, from lung or breast primary cancers - and associated w/ different genetic alterations, to reveal distinct immune cell landscapes and phenotypes ⏬ https://t.co/b4j2P5phI9 #openaccess #TME”

Twitter
Should it really cost $950 to attend a meeting virtually? I'm all for hybrid conferences and trying not to set the planet on fire but I find it hard to believe they can cost so much to attend?

RT @[email protected]

I am looking for a T cell immunologist who loves flow cytometry! Come and do a postdoc in my friendly, collaborative lab. Job listing here!

https://www.immunology.org/careers/bsi-jobs-board

🐦🔗: https://twitter.com/GwyerFindlay/status/1612827782358212608

BSI jobs board | British Society for Immunology

RT @[email protected]

Very excited to share a new paper from my lab: using a set chromosome-engineering tools, we show that cancers are “addicted” to aneuploidy. If you genetically eliminate single aneuploid chromosomes, cancer cells totally lose their malignant potential!
https://www.biorxiv.org/content/10.1101/2023.01.09.523344v1

🐦🔗: https://twitter.com/JSheltzer/status/1612856285850128390

Opinion: The Problem with Researchers Hoarding Resources

For too long, some scientists have acted like Gollums of the ivory tower, guarding precious study sites, model organisms, and even entire fields of inquiry.

The Scientist Magazine®
Loved this interview about experiencing academia from a childhood of poverty - lots to reflect on as to how to increase access for all in academia https://www.timeshighereducation.com/people/interview-katriona-osullivan
Interview with Katriona O’Sullivan

A widening access alumnus and practitioner on the difficulties of coming into academia from a background of poverty

Times Higher Education (THE)
2022 ended with a medical emergency (treated quickly) for my dad and stranded in a car breakdown - celebrating the end of the year with aplomb! Here's to 2023 with my growing boys, fantastic lab and wonderful friends, happy new year 🎇

A great read to close out the year: radially expanding populations decrease competition as they grow (because of expanding available area or volume), which facilitates the survival of unfit mutants and downstream acquisition of compensatory mutations. This can underlie the evolution of resistance to treatment in bacterial biofilms and solid tumors.

#evolution #amr #cancer

https://www.nature.com/articles/s41467-022-35484-y

Evolutionary rescue of resistant mutants is governed by a balance between radial expansion and selection in compact populations - Nature Communications

Antibiotic and anti-cancer therapy are challenged by mutation-mediated treatment resistance despite many mutations being maladaptive. Here, the authors introduce a system that shows how the probability of the long-term persistence of drug-resistant mutant lineages can be increased in dense microbial populations by acquiring multiple mutations.

Nature