VicidominiLab
#quantum is here! Why not collect #fluorescence #photon-by-photon in your laser-scanning #microscope? We developed the #BrightEyes_TTM, an #opensource data acquisition system able to do it!
https://www.nature.com/articles/s41467-022-35064-0
@IITalk@twitter.com @ERC_Research@twitter.com @RNA_iit@twitter.com @MSCActions@twitter.com #BrightEyes_ERC
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The BrightEyes-TTM as an open-source time-tagging module for democratising single-photon microscopy - Nature Communications

The authors developed an open-source, low-cost, multi-channel time-tagging module for fluorescence lifetime image scanning microscopy and correlation spectroscopy that can tag in parallel multiple single-photon events with 30 ps precision.

Nature
Dec 7, 2022 at 8:22amWeb
Show threadVicidominiLabDec 7, 2022
Our time-tagging #DAQ module can collect single-photon signals from 25 independent channels and reference signals from 3 channels. We showed how this module combined with a #SPAD array allows us to perform #FLISM and #FLFS. (2/5)
#imagescanningmicroscopy #fluorescence #lifetime
Show threadVicidominiLabDec 7, 2022
We characterized the #BrightEyes_TTM. We can reach a single-shot precision of 30 ps, 4 ns dead-time, and an "infinite" range in all channels, with a total flux of up to 125 MHz. (3/5)
#TCSPC #antibunching #quantum #microscopy #FPGA
#coding #LIDAR
Show threadVicidominiLabDec 7, 2022
Fluorescence has never been so informative! Thanks to the synergy between the #BrightEyes_TTM and the #SPAD array detector, we can perform #FLFS on living cells to simultaneously follow different dynamics parameters and fluorescence lifetime. (4/5)
#singlephotonmicroscopy