Phys.orgApr 13, 2023

Referenced link: https://phys.org/news/2023-04-uncovering-hidden-mitochondrial-mutations-cells.html
Discuss on https://discu.eu/q/https://phys.org/news/2023-04-uncovering-hidden-mitochondrial-mutations-cells.html

Originally posted by Phys.org / @physorg_com: http://nitter.platypush.tech/physorg_com/status/1646562028197236737#m

Uncovering hidden #mitochondrialmutations in #singlecells @kaust_news https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gkad209/7103214 https://phys.org/news/2023-04-uncovering-hidden-mitochondrial-mutations-cells.html

Uncovering hidden mitochondrial mutations in single cells

A high-throughput single-cell single-mitochondrial genome sequencing technology known as iMiGseq has provided new insights into mutations of mitochondrial DNA (mtDNA) and offers a platform for assessing mtDNA editing strategies and genetic diagnosis of embryos prior to their implantation.

Phys.org
Thomas SandmannApr 9, 2023
Very cool preprint by Adam P Cribbs's group: "Correcting PCR amplification errors in unique molecular identifiers to generate absolute numbers of sequencing molecules." https://www.biorxiv.org/content/10.1101/2023.04.06.535911v1 with lots of innovative ideas to a) measure and b) correct PCR induced errors in RNA-seq experiments. #rnaseq #ngs #singlecells #compbio #illumina #nanopore
Show threadCostas AnastassiouDec 27, 2022
Back in 2016, together with Jonathan Ting we thought looking at #singlecells in the living, resected hippocampal tissue excised from #epilepsy #patients was such a unique opportunity to study the #disease and, ultimately, make a #difference in the lives of #patients.
Christian TidonaDec 23, 2022

Are you seeing what I am seeing?

Then it's definitely time for a break!

#HappyHolidays #singlecells