Daniel Huson introduces displacement-optimized tanglegrams (DO-tanglegrams), a new approach that applies equally to trees and rooted phylogenetic networks, performing better than cophylo on trees and then NN-tanglegram on networks.

๐Ÿ”— https://doi.org/10.1093/molbev/msag066

#evobio #molbio #compbio

McArthur et al. present piqtree, an easy to use, open-source Python package that provides Python script-based control of IQ-TREEโ€™s phylogenetic inference engine.

๐Ÿ”— https://doi.org/10.1093/molbev/msag061

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@sishuowang & Meade introduce phyloHessian to enable the use of complex mixture substitution models in molecular dating. Empirical analysis of ancient symbiont lineages leads to a revised understanding of their host association origins.

๐Ÿ”— https://doi.org/10.1093/molbev/msag039

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Robbins, Liu & Kelly present RECUR, a method for identifying recurrent amino acid substitutions from multiple sequence alignments that is fast, easy to use, and scalable to thousands of sequences.

๐Ÿ”— https://doi.org/10.1093/molbev/msag036

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Deng et al. present TreeProfiler, a tool for automated annotation and interactive exploration of hundreds of features along large gene and species trees, with seamless summarization of mapped traits at internal nodes.

๐Ÿ”— https://doi.org/10.1093/molbev/msag028

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Martรญ-Gรณmez et al. developed gpmap-tools, integrating models for inference, phenotypic imputation, and error estimation from multiplex assays of variant effect data or natural sequences in the presence of genetic interactions.

๐Ÿ”— https://doi.org/10.1093/molbev/msag023

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Anchieri et al. benchmark the inference of selection with aDNA-like time series datasets, showing that ApproxWF can accurately estimate selection with datasets of โˆผ100 individuals when selection is strong.

๐Ÿ”— https://doi.org/10.1093/gbe/evaf234

#genome #evolution #compbio

Ramos-Gonzรกlez et al. present PharaohFUN, a web application designed for the evolutionary and functional analysis of protein sequences in photosynthetic eukaryotes, leveraging orthology relationships.

๐Ÿ”— https://doi.org/10.1093/molbev/msag011

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Malik et al. present the web-based Structome-AlignViewer, for evaluating structure-aware alignments through spatial mapping of alignment columns to protein structures, and quantitative confidence scoring.

๐Ÿ”— https://doi.org/10.1093/gbe/evag004

#genome #evolution #compbio

Shankar et al. present the updated MicrobeTrace 2.0 as a next-generation, interoperable tool for genomic epidemiology and data-driven public health response.

๐Ÿ”— https://doi.org/10.1093/molbev/msaf334

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