#Statue #in #Novorossiysk #of #Gesha #Kozodoyev , #the #character #in #the #famous #Soviet #film #The #Diamond #Arm (1969), #played #by #Andrei #Mironov .

#During #high #tide , #the #bottom #of #the #statue #disappears #under #water , #which #replicates #the #scene #in #the #movie #when #Gesha #walks #on #the #water #after #a #boy #fisherman , #whom #he #mistook #for #an #angel

Cheeky Computer Scientist replicates Quantum Factoring record with a dog [pdf]

https://eprint.iacr.org/2025/1237.pdf

#HackerNews #Cheeky #Computer #Scientist #replicates #Quantum #Factoring #record #with #a #dog #[pdf] #quantumfactoring #computer #science #research #doglover #innovation

Just reading this very interesting paper on how many #replicates are needed for appropriate analysis of bulk #RNAseq data and comparing tools for DE gene expression.

#bioinformatics #article #goodread

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878611/

From the abstract

With three biological replicates, nine of the 11 tools evaluated
found only 20%–40% of the significantly differentially expressed (SDE) genes identified with the full set of 42 clean replicates.
This rises to >85% for the subset of SDE genes changing in expression by more than fourfold. To achieve >85% for all SDE genes regardless of fold change requires more than 20 biological replicates.