Mic 🎤: "New Study: The Unprocessed Red Meat Science is Biased"
https://www.youtube.com/shorts/xvoz-wjrXP8
#meat #processedMeat #unprocessedMeat #UPF #cancer #oncogenic #badScience #pseudoscience #meatIndustry
A fun paper to share:
"Cancer risk across mammals"
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We show that the phylogenetic distribution of cancer mortality is associated with diet, with carnivorous mammals (especially mammal-consuming ones) facing the highest cancer-related mortality. Moreover, we provide unequivocal evidence for the body size and longevity components of Peto’s paradox by showing that cancer mortality risk is largely independent of both body mass and adult life expectancy across species. These results highlight the key role of life-history evolution in shaping cancer resistance and provide major advancements in the quest for natural anticancer defences.
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These results indicate that a carnivorous diet has significant costs in terms of heightened oncogenic predisposition across mammals, particularly for diets high in mammalian prey.
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edit: https://www.nature.com/articles/s41586-021-04224-5 forgot the link 🤪
#cancer #meat #carnivore #mammal #mammalian #diet #oncogenic #mammals
https://www.mdpi.com/1422-0067/24/9/7803
[according to the growing interest in virus-induced pathologies,
a controversial role for the severe acute respiratory syndrome coronavirus 2
in holding an #oncogenic potential is debated as advertised by recent literature.
Hence, SARS-CoV-2 may favor tumor progression by acting on metabolic reprogramming to stimulate #cell replication]
Some viruses are known to be associated with the onset of specific cancers. These microorganisms, oncogenic viruses or oncoviruses, can convert normal cells into cancer cells by modulating the central metabolic pathways or hampering genomic integrity mechanisms, consequently inhibiting the apoptotic machinery and/or enhancing cell proliferation. Seven oncogenic viruses are known to promote tumorigenesis in humans: human papillomavirus (HPV), hepatitis B and C viruses (HBV, HCV), Epstein-Barr virus (EBV), human T-cell leukemia virus 1 (HTLV-1), Kaposi sarcoma-associated herpesvirus (KSHV), and Merkel cell polyomavirus (MCPyV). Recent research indicates that SARS-CoV-2 infection and COVID-19 progression may predispose recovered patients to cancer onset and accelerate cancer development. This hypothesis is based on the growing evidence regarding the ability of SARS-CoV-2 to modulate oncogenic pathways, promoting chronic low-grade inflammation and causing tissue damage. Herein, we summarize the main relationships known to date between virus infection and cancer, providing a summary of the proposed biochemical mechanisms behind the cellular transformation. Mechanistically, DNA viruses (such as HPV, HBV, EBV, and MCPyV) encode their virus oncogenes. In contrast, RNA viruses (like HCV, HTLV-1) may encode oncogenes or trigger host oncogenes through cis-/-trans activation leading to different types of cancer. As for SARS-CoV-2, its role as an oncogenic virus seems to occur through the inhibition of oncosuppressors or controlling the metabolic and autophagy pathways in the infected cells. However, these effects could be significant in particular scenarios like those linked to severe COVID-19 or long COVID. On the other hand, looking at the SARS-CoV-2─cancer relationship from an opposite perspective, oncolytic effects and anti-tumor immune response were triggered by SARS-CoV-2 infection in some cases. In summary, our work aims to recall comprehensive attention from the scientific community to elucidate the effects of SARS-CoV-2 and, more in general, β-coronavirus infection on cancer susceptibility for cancer prevention or supporting therapeutic approaches.
"The resulting CYPA:drug:KRASG12C #tricomplex inactivated #oncogenic signaling and led to tumor regressions in multiple human cancer models. This inhibitory strategy can be used to target additional #KRAS mutants and other undruggable #cancer drivers."
Is #SARSCoV2 an oncogenic virus
Deciphering the Relationship between SARS-CoV-2 and Cancer.
Recent research indicates that #SARSCoV2 infection and #COVID19 progression may predispose recovered patients to cancer onset and accelerate cancer development.
SARSCoV2's role as an oncogenic virus occurs by inhibiting oncosuppressors or controlling the metabolic and autophagy pathways TRP the infected cells.
#Kovd #Oncosuppressors #Cancer #Oncogenic
https://www.facebook.com/groups/1632045180447285/permalink/3458036944514757/
“Is SARS-CoV-2 an oncogenic virus?’
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9361571/
In the letter to the editor in the Journal of Infection, the writers noted Wu and Gao had indicated #covid19 might be associated with endometrial cancer.
The writers point out similarities to pathology associated with #oncogenic properties of Epstein Barr Virus and Hepatitis B.
Worth keeping an eye on.
Scientific Frontline
VeganPizza69 ⓋⒶ
Lumière Claire
katch wreck
The EMBO Journal
Zoomers of the Sunshine Coast 🇨🇦
Tui22