@cyrilpedia Their observations show no change in the percentage of total #tumor associated #macrophages (TAMs) in the tumor tissue but a markedly increased percentage of NOS2+TAMs with no significant changes in arginase I expression...raising the question, which cell type would be the corresponding human counterpart? Macrophage or #monocyte ?

#Monocyte deposits VEGF/CXCL12-containing #Migrasome to stimulate CAM #Angiogenesis, as well as reinforce monocyte recruitment

Wonder if this fascinating cascade is also functional in tissue regeneration?😆

Dr. Li Yu lab Nature Cell Bio 2022
https://www.nature.com/articles/s41556-022-01026-3

Monocytes deposit migrasomes to promote embryonic angiogenesis - Nature Cell Biology

Zhang et al. have data suggesting that, in the chicken embryo, monocytes foster a pro-angiogenic microenvironment in advance of angiogenesis by depositing migrasomes enriched in angiogenic factors.

Nature