New study details how #starving #cells hijack #protein #transport stations.

#ER #exit_sites #lysosomes #ALG2 #COPII #microautophagy

https://phys.org/news/2024-04-starving-cells-hijack-protein-stations.html

"Here, we demonstrate that damaged #lysosomal #membranes are repaired by #microautophagy (a process termed “microlysophagy”) and identify key regulators of the first and last steps. We reveal the AGC #kinase STK38 as a novel microlysophagy regulator...microlysophagy is regulated by STK38 and GABARAPs and could be essential for maintaining lysosomal integrity and preventing #aging."

https://www.embopress.org/doi/full/10.15252/embr.202357300

#autophagy