первый российский человекоподобный робот Сосайдол #sosAidol

#AIdol #aldol

Happy to share my latest #research with Prof P. Chiu (University of #HongKong) and E. Krenske (University of #Queensland):
Reductive #Aldol Reaction of cyclic enones. I personally love this work because it allows the construction of aldol products that were previously difficult to achieve. If the enolate is cyclic, an (E)-enolate is automatically formed. In most cases this leads to an anti aldol reaction, but in our case we get the syn product.

#chemistry

Read more: https://chemistry-europe.onlinelibrary.wiley.com/doi/abs/10.1002/chem.202401485

Researchers (Rahul Choudhury et al.) from the Academy of Scientific and Innovative Research in #India reported in the journal #OrganicLetters the total synthesis of benzo[g]isochromene stereodiads. Their synthesis using a TiCl4 promoted #Aldol coupling showed that the previously reported absolute structure did not agree with the structure of the natural product and a revision was suggested.

https://pubs.acs.org/doi/10.1021/acs.orglett.4c00553

#chemistry #TotalSynthesis