Chemistry ResearchResearchers (Rahul Choudhury et al.) from the Academy of Scientific and Innovative Research in #India reported in the journal #OrganicLetters the total synthesis of benzo[g]isochromene stereodiads. Their synthesis using a TiCl4 promoted #Aldol coupling showed that the previously reported absolute structure did not agree with the structure of the natural product and a revision was suggested.
Synthesis of rakicidin C reported by Varinder Aggarwal and colleagues (University of #Bristol, #UK) in the journal #OrganicLetters. Using their iterative assembly method and various coupling strategies yielding a highly convergent synthetic route.