Mastodawn

ScienceOpen Jul 22, 2025

🧠✨ #WorldBrainDay recommended reading: 'Sleep Duration and Cognitive Function: The Akershus Cardiac Examination 1950 Study' - a Karger: Neurology and Neuroscience article on #ScienceOpen:

🔗 https://www.scienceopen.com/document?vid=46310254-77d3-4cad-8d0c-c19ef2a07887

#WorldBrainDay2025 #WBD2025 #BrainHealth #BrainHealthMatters #BrainHealthForAllAges

Sleep Duration and Cognitive Function: The Akershus Cardiac Examination 1950 Study

<p xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" dir="auto" id="d5231462e307"> <b> <i>Introduction:</i> </b> Sleep duration is proposed as a lifestyle-related risk factor for cognitive impairment. We investigated the association between sleep duration and cognitive function in a large population-based cohort aged 62–65 years. <b> <i>Methods:</i> </b> Cross-sectional analyses from the Akershus Cardiac Examination 1950 Study. Linear and nonlinear models were conducted to explore the association between self-reported sleep duration and cognitive function, adjusted for established risk factors for cognitive impairment. <b> <i>Results:</i> </b> We included 3,348 participants, mean age (SD) was 63.9 ± 0.6 years, 48.2% were women, and 47.9% had education >12 years. Mean sleep duration (SD) was 7.0 ± 1.0 h, and 10.2% had abnormal sleep duration (<6 or >8 h). Individuals reporting <6 h or >8 h of sleep scored significantly lower on MoCA test and delayed recall trial in adjusted analysis. <b> <i>Conclusions:</i> </b> Sleep duration showed an inverted U-shaped association with global cognitive function and memory, suggesting that both shortened and prolonged sleep are related to adverse brain health. </p>

ScienceOpen

ScienceOpen Jul 22, 2025

🧠✨ #WorldBrainDay recommended reading: 'From Dementia to Eumentia: A New Approach to Dementia Prevention' - a Karger: Neurology and Neuroscience article on #ScienceOpen:

🔗 https://www.scienceopen.com/document?vid=50b51923-2551-431d-94a9-d99bc064919d

#WorldBrainDay2025 #WBD2025 #BrainHealth #BrainHealthMatters #BrainHealthForAllAges

From Dementia to Eumentia: A New Approach to Dementia Prevention

<p class="first" id="d4786883e156"> <b> <i>Background:</i> </b> During the past 40 years, dementia prevention approaches have ranged from searching for a drug to prevent progression to Alzheimer’s disease to preventing dementia through multidomain lifestyle interventions. <b> <i>Current Approaches:</i> </b> The search for a silver bullet has yielded good science but no clinical results. The multi-model lifestyle intervention approach has shown encouraging results. The largest proportion of resources in prevention have been devoted to finding a drug to prevent, mitigate, or delay what is being called “Alzheimer’s disease of late onset.” The reality is that Alzheimer’s pathology is common among the elderly, but it seldom only occurs alone. The only treatable and preventable pathology currently is vascular. Hence arose the concept of “vascular cognitive impairment” meaning any vascular cause or risk factor associated with cognitive impairment. The majority of cases of cognitive impairment in the elderly have a vascular component that is treatable and preventable and identifiable by several means, including a simple ischemic score. <b> <i>Conclusion:</i> </b> Since environmental, socioeconomic, and individual risk factors contribute to dementia, we proposed a Comprehensive, Customized, Cost-effective APProach (the CCC-APP) implemented in actionable units with the focus on promoting brain health (eumentia). <b> <i>Key Messages:</i> </b> We should implement dementia prevention approaches in actionable units around optimal brain health or eumentia. Heart disease, stroke, and dementia share mostly the same risk and protective factors; thus, their joint prevention is desirable. We need a comprehensive, customized, and cost-effective approach to joint prevention of stroke, heart disease, and dementia. We call for literal and virtual meetings of researchers of all the relevant disciplines to work on operational definitions and interdisciplinary collaborations. </p>

ScienceOpen

ScienceOpen Jul 22, 2025

🧠✨ #WorldBrainDay recommended reading: 'The Real-World Usability, Feasibility, and Performance Distributions of Deploying a Digital Toolbox of Computerized Assessments to Remotely Evaluate Brain Health: Development and Usability Study' - an article from JMIR Publications on #ScienceOpen:

🔗 https://www.scienceopen.com/document?vid=e12b6dbe-7e79-422e-bb2e-234400b80fae

#WorldBrainDay2025 #WBD2025 #BrainHealth #BrainHealthMatters #BrainHealthForAllAges

The Real-World Usability, Feasibility, and Performance Distributions of Deploying a Digital Toolbox of Computerized Assessments to Remotely Evaluate Brain Health: Development and Usability Study

<div xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" class="section"> <a class="named-anchor" id="d3019020e194">  </a> <h5 class="section-title" id="d3019020e195">Background</h5> <p dir="auto" id="d3019020e197">An ongoing global challenge is managing brain health and understanding how performance changes across the lifespan. </p> </div><div xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" class="section"> <a class="named-anchor" id="d3019020e199">  </a> <h5 class="section-title" id="d3019020e200">Objective</h5> <p dir="auto" id="d3019020e202">We developed and deployed a set of self-administrable, computerized assessments designed to measure key indexes of brain health across the visual and auditory sensory modalities. In this pilot study, we evaluated the usability, feasibility, and performance distributions of the assessments in a home-based, real-world setting without supervision. </p> </div><div xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" class="section"> <a class="named-anchor" id="d3019020e204">  </a> <h5 class="section-title" id="d3019020e205">Methods</h5> <p dir="auto" id="d3019020e207">Potential participants were untrained users who self-registered on an existing brain training app called BrainHQ. Participants were contacted via a recruitment email and registered remotely to complete a demographics questionnaire and 29 unique assessments on their personal devices. We examined participant engagement, descriptive and psychometric properties of the assessments, associations between performance and self-reported demographic variables, cognitive profiles, and factor loadings. </p> </div><div xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" class="section"> <a class="named-anchor" id="d3019020e209">  </a> <h5 class="section-title" id="d3019020e210">Results</h5> <p dir="auto" id="d3019020e212">Of the 365,782 potential participants contacted via a recruitment email, 414 (0.11%) registered, of whom 367 (88.6%) completed at least one assessment and 104 (25.1%) completed all 29 assessments. Registered participants were, on average, aged 63.6 (SD 14.8; range 13-107) years, mostly female (265/414, 64%), educated (329/414, 79.5% with a degree), and White (349/414, 84.3% White and 48/414, 11.6% people of color). A total of 72% (21/29) of the assessments showed no ceiling or floor effects or had easily modifiable score bounds to eliminate these effects. When correlating performance with self-reported demographic variables, 72% (21/29) of the assessments were sensitive to age, 72% (21/29) of the assessments were insensitive to gender, 93% (27/29) of the assessments were insensitive to race and ethnicity, and 93% (27/29) of the assessments were insensitive to education-based differences. Assessments were brief, with a mean duration of 3 (SD 1.0) minutes per task. The pattern of performance across the assessments revealed distinctive cognitive profiles and loaded onto 4 independent factors. </p> </div><div xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" class="section"> <a class="named-anchor" id="d3019020e214">  </a> <h5 class="section-title" id="d3019020e215">Conclusions</h5> <p dir="auto" id="d3019020e217">The assessments were both usable and feasible and warrant a full normative study. A digital toolbox of scalable and self-administrable assessments that can evaluate brain health at a glance (and longitudinally) may lead to novel future applications across clinical trials, diagnostics, and performance optimization. </p> </div>

ScienceOpen

SCAB Pharmacy Limited Jul 22, 2025

𝗪𝗼𝗿𝗹𝗱 𝗕𝗿𝗮𝗶𝗻 𝗗𝗮𝘆 𝟮𝟬𝟮𝟱 – 𝗕𝗿𝗮𝗶𝗻 𝗛𝗲𝗮𝗹𝘁𝗵 𝗳𝗼𝗿 𝗔𝗹𝗹 𝗔𝗴𝗲𝘀 🧠�*

Today, on 22nd July, we observe World Brain Day to raise awareness about brain diseases and promote brain health at every stage of life—from before birth to old age.

𝗗𝗶𝗱 𝘆𝗼𝘂 𝗸𝗻𝗼𝘄?
Non-communicable neurological diseases like stroke, migraines, and epilepsy are major contributors to disability worldwide. Yet, funding and attention often fall short compared to other diseases. This day reminds us why brain health needs global focus.

𝗛𝗼𝘄 𝗰𝗮𝗻 𝘆𝗼𝘂 𝗽𝗿𝗼𝘁𝗲𝗰𝘁 𝘆𝗼𝘂𝗿 𝗯𝗿𝗮𝗶𝗻?
- Get at least 7 hours of sleep regularly
- Exercise daily (aim for 2 hours)
- Wear helmets and seatbelts for safety
- Manage mental health: seek help for anxiety or depression
- Reduce screen time before bed
- Avoid caffeine and nicotine 6 hours before sleep
- Eat brain-friendly foods: green veggies, nuts, seafood, seeds

Let’s commit to brain health for all ages—because a healthy brain means a healthier, happier life.

#WorldBrainDay2025 #BrainHealthForAllAges #BrainAwareness #NeurologicalHealth #StrokeAwareness #MentalHealthMatters #HealthyBrainTips #BrainCare #PreventBrainDisorders #SCABPharmacy #StayHealthy #BrainHealth