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Mutations in #microtubule regulatory protein Katnal2 have been linked to #autism. This study finds that loss of Katnal2 in mice leads to autism-related phenotypes, driven in part by altered #ciliary function in the lateral #ventricles #PLOSBiology https://plos.io/4aezHNy
Loss of Katnal2 leads to ependymal ciliary hyperfunction and autism-related phenotypes in mice

Mutations in the microtubule regulatory protein Katnal2 have been linked to autism. This study finds that loss of Katnal2 in mice leads to autism-related phenotypes, which are driven in part by altered ciliary function in the lateral ventricles.

All heart tissue is not made the same. The left ventricle is commonly considered the most important during development and for blood flow and is at most risk of disease and disorder.

Using stem cells, Imperial College London scientists have made a method to specifically develop left ventricle heart muscle cells for general medicine testing and disease treatment studies.

#Medicine #Science #Heart #Muscle #Stemcells #Ventricles #Disease #Biology #Biotechnology #Scicomm

https://www.sciencedirect.com/science/article/pii/S2667237523000759